Variable | In-hospital mortality | Postdischarge mortality (90 d) | ||
---|---|---|---|---|
Adjusted HR* (95% CI) | p value | Adjusted HR† (95% CI) | p value | |
Age, yr | ||||
< 60 (ref) | 1.00 (ref) | − | − | − |
61–70 | 1.24 (0.79–1.95) | 0.4 | − | − |
71–80 | 2.30 (1.53–3.47) | < 0.0001 | − | − |
> 80 | 4.22 (2.89–6.17) | < 0.0001 | − | − |
Methicillin resistance | ||||
No | − | − | 1.00 (ref) | − |
Yes | − | − | 1.74 (1.04–2.89) | 0.03 |
Sepsis | ||||
No | 1.00 (ref) | − | − | − |
Yes | 1.44 (1.04–1.99) | 0.03 | − | − |
Admission to intensive care unit | ||||
No | 1.00 (ref) | − | − | − |
Yes | 2.35 (1.78–3.11) | < 0.0001 | − | − |
Hepatic failure | ||||
No | 1.00 (ref) | − | 1.00 (ref) | − |
Yes | 2.20 (1.25–3.88) | 0.01 | 5.42 (1.60–18.35) | 0.01 |
Prolonged ventilation > 21 d | ||||
No | − | − | − | − |
Yes | − | − | − | − |
Cerebrovascular disease | ||||
No | − | − | 1.00 (ref) | − |
Yes | − | − | 2.16 (1.21–3.86) | 0.01 |
COPD | ||||
No | − | − | 1.00 (ref) | − |
Yes | − | − | 2.43 (1.28–4.61) | 0.01 |
Metastatic cancer | ||||
No | 1.00 (ref) | − | 1.00 (ref) | − |
Yes | 2.79 (1.90–4.10) | < 0.0001 | 5.32 (2.80–10.07) | < 0.0001 |
Note: CI = confidence interval, COPD = chronic obstructive pulmonary disorder, HR = hazard ratio, ref = reference. *Adjusted for age, sepsis, admission to the intensive care unit, hepatic failure and metastatic cancer. †Adjusted for methicillin resistance, hepatic failure, cerebrovascular disease, COPD and metastatic cancer.