| Factor | HR (95% CI) |
|---|---|
| Year of inclusion | |
| 2000 | 1 (referent) |
| 2001 | 0.93 (0.91–0.95) |
| 2002 | 0.85 (0.83–0,87) |
| 2003 | 0.78 (0.76–0.79) |
| 2004 | 0.69 (0.68–0.71) |
| 2005 | 0.62 (0.60–0.63) |
| 2006 | 0.50 (0.49–0.51) |
| 2007 | 0.35 (0.34–0.36) |
| Age, yr | |
| 50–54 | 1 (referent) |
| 55–59 | 1.08 (1.07–1.10) |
| 60–64 | 1.17 (1.15–1.19) |
| 65–69 | 1.21 (1.19–1.22) |
| 70–74 | 1.12 (1.10–1.14) |
| 75–79 | 0.91 (0.89–0.93) |
| Sex | |
| Male | 1 (referent) |
| Female | 0.90 (0.89–0.91) |
| Comorbidity (JH ADG) | 1.25 (1.23–1.28) |
| Socioeconomic status* | |
| Urban bottom 20th ‰ | 1 (referent) |
| Urban 60th–80th ‰ | 1.24 (1.21–1.26) |
| Urban 40th–60th ‰ | 1.04 (1.02–1.06) |
| Urban 20th–40th ‰ | 1.04 (1.02–1.05) |
| Urban top 20th ‰ | 1.02 (1.01–1.04) |
| Rural | 1.12 (1.10–1.14) |
| Setting | |
| Hospital | 1 (referent) |
| Nonhospital | 1.05 (1.02–1.07) |
| Open access < 36 mo | |
| No | 1 (referent) |
| Yes | 1.24 (1.21–1.26) |
| Open access ≥ 36 mo | |
| No | 1 (referent) |
| Yes | 1.55 (1.51–1.59) |
| Specialty | |
| Gastroenterologist | 1 (referent) |
| General surgeon | 1.27 (1.25–1.28) |
| Internist | 1.05 (1.03–1.06) |
| Other | 1.21 (1.17–1.25) |
| Main practice location | |
| Hospital | 1 (referent) |
| Private clinic/office | 1.26 (1.22–1.30) |
| Mixed | 1.00 (0.98–1.01) |
Note: CI = confidence interval, HR = hazard ratio, JH ADG = John Hopkins aggregated diagnosis groups. *Socioeconomic status is presented as the median neighbourhood income quintile within the patient’s postal code area unless rural.