| Month | Raw values no.* (mean ± SD) | Maximum likelihood,† mean ± SE | Maximum likelihood change from baseline,† mean (95% CI) | p value |
|---|---|---|---|---|
| Age-sex standardized VO2max percentile | ||||
| 0 | 287 (46.8 ± 24.0) | 46.9 ± 1.2 | ||
| 3 | 238 (59.7 ± 22.4) | 60.5 ± 1.1 | 13.6 (11.7-15.6) | < 0.0001 |
| 12 | 182 (63.0 ± 20.6) | 62.5 ± 1.2 | 15.6 (13.3-17.9) | < 0.0001 |
| Canadian Healthy Eating Index (range 0-100) | ||||
| 0 | 284 (57.9 ± 14.2) | 57.9 ± 0.8 | ||
| 3 | 256 (68.6 ± 12.4) | 68.5 ± 0.8 | 10.6 (8.8-12.4) | < 0.0001 |
| 12 | 209 (68.0 ± 14.1) | 67.5 ± 0.9 | 9.6 (7.6-11.6) | < 0.0001 |
| Mediterranean diet score range (0-14) | ||||
| 0 | 207 (4.7 ± 1.6) | 4.8 ± 0.1 | ||
| 3 | 233 (6.1 ± 2.0) | 6.2 ± 0.1 | 1.4 (1.1-1.6) | < 0.0001 |
| 12 | 209 (6.2 ± 1.9) | 6.2 ± 0.1 | 1.4 (1.1-1.6) | < 0.0001 |
Note: CI = confidence interval, SD = standard deviation, SE = standard error.
*No. of patients where the variable was captured.
†The maximum likelihood mean and change use all available data to estimate the expected values using within patient correlations between outcomes and time points. The maximum likelihood mean is estimated for a 60-year-old assuming even numbers of men and women.