| Variable | Univariate hazard ratio (95% CI) | Adjusted hazard ratio (95% CI) |
|---|---|---|
| Treatment group (postchemotherapy v. exception patient) | 1.05 (0.72-1.52) | 0.89 (0.57-1.38) |
| Age at initiation of abiraterone therapy (≥ 70 v. < 70 yr) | 0.63 (0.41-0.99) | 0.72 (0.44-1.19) |
| Bone-targeted therapy (yes v. no) | 0.94 (0.62-1.41) | 0.90 (0.58-1.39) |
| Palliative radiotherapy* (yes v. no) | 2.80 (1.91-4.11) | 2.80 (1.75-4.50) |
| Proximity to radiation oncology centre (yes v. no) | 0.96 (0.65-1.42) | 0.89 (0.58-1.39) |
| Rural residence (yes v. no) | 0.93 (0.59-1.45) | 0.92 (0.56-1.50) |
| Diabetes (yes v. no) | 1.45 (0.97-2.16) | 1.33 (0.85-2.08) |
| Dyslipidemia (yes v. no) | 0.90 (0.63-1.29) | 0.89 (0.60-1.33) |
| Hypertension (yes v. no) | 0.95 (0.63-1.42) | 0.79 (0.49-1.26) |
| Coronary heart disease (yes v. no) | 1.08 (0.73-1.60) | 1.01 (0.65-1.59) |
| Chronic heart failure (yes v. no) | 2.15 (1.30-3.56) | 1.88 (1.03-3.40) |
| Cerebrovascular disease (yes v. no) | 1.33 (0.54-3.25) | 1.81 (0.71-4.62) |
| Arrhythmia (yes v. no) | 1.28 (0.82-2.02) | 1.02 (0.60-1.74) |
Note: CI = confidence interval.
*Time-dependent variable.