| Characteristic | No. (%) of patients | |
|---|---|---|
| IgM-positive or IgG-positive n = 38 | IgM-positive n = 29 | |
| Sign/symptom | ||
| Systemic | ||
| Any | 30 (79) | 25 (86) |
| Fever (reported or objective) | 20 (53) | 17 (59) |
| Fatigue | 18 (47) | 14 (48) |
| Headaches | 12 (32) | 10 (34) |
| Anorexia | 5 (13) | 5 (17) |
| Lymphadenopathy | 3 (8) | 3 (10) |
| Malaise | 9 (24) | 7 (24) |
| Lethargy | 2 (5) | 1 (3) |
| Cutaneous | ||
| Any | 27 (71) | 23 (79) |
| Erythema migrans | 15 (39) | 14 (48) |
| Cellulitis | 2 (5) | 2 (7) |
| Other | 10 (26) | 7 (24) |
| Musculoskeletal | ||
| Any | 20 (53) | 13 (45) |
| Myalgia | 15 (39) | 12 (41) |
| Arthralgia | 7 (18) | 4 (14) |
| Migratory pains | 3 (8) | 3 (10) |
| Arthritis | 4 (10) | 1 (3) |
| Neurological | ||
| Any | 7 (18) | 5 (17) |
| Nuchal rigidity | 2 (5) | 1 (3) |
| Facial paralysis | 4 (10) | 3 (10) |
| Polyradiculopathy | 1 (3) | 1 (3) |
| Cardiac | ||
| Any | 2 (5) | 2 (7) |
| Atrioventricular block | 2 (5) | 2 (7) |
| Ophthalmic | ||
| Any | 1 (3) | 1 (3) |
| Conjunctivitis | 1 (3) | 1 (3) |
| History | ||
| Reported travel in New England | 3 (8) | 3 (10) |
| Tick bite reported* | 12 (32) | 11 (38) |
*No ticks were brought for analysis.