| Outcome | Emergency physician | Family physician | p value |
|---|---|---|---|
| Opioid toxicity | |||
| No. (%) of patients | 172 (0.5) | 129 (0.3) | - |
| Rate per 100 person-years | 0.25 | 0.14 | - |
| Hazard ratio (95% CI) | 1.77 (1.41-2.22) | Reference | < 0.001 |
| Dosage escalation | |||
| No. (%) of patients | 46 (0.1) | 301 (0.7) | - |
| Rate per 100 person-years | 6.19 | 7.67 | - |
| Hazard ratio (95% CI) | 1.25 (0.91-1.72) | Reference | > 0.05 |
Note: CI = confidence interval.