Table 1:

Baseline demographic and health characteristics of women in the general Ontario population aged 19–69 years between July 2003 and July 2012, comparing those with bipolar disorder or schizophrenia to those without

CharacteristicGroup; no. (%) of women*Standardized difference
Overall
n = 1 245 457
Exposure
n = 119 948
Matched
n = 1 125 509
Age, yr, median (IQR)42 (29–52)42 (30–52)42 (29–52)0.02
Income quintile
 1 (lowest)298 115 (23.9)29 896 (24.9)268 219 (23.8)0.03
 2265 181 (21.3)25 548 (21.3)239 633 (21.3)< 0.001
 3236 935 (19.0)22 443 (18.7)214 492 (19.1)0.01
 4224 190 (18.0)21 186 (17.7)203 004 (18.0)0.01
 5 (highest)219 010 (17.6)20 601 (17.2)198 409 (17.6)0.01
 Missing2026 (0.2)274 (0.2)1752 (0.2)0.02
Residence
 Urban1 131 150 (90.9)108 389 (90.3)1 022 761 (90.9)0.01
 Rural113 879 (9.1)11 496 (9.6)102 383 (9.1)0.02
 Missing428 (0.03)63 (0.1)365 (0.03)0.01
Charlson Comorbidity Index score
 0178 386 (14.3)24 961 (20.8)153 425 (13.6)0.19
 118 447 (1.5)3451 (2.9)14 996 (1.3)0.11
 210 749 (0.9)1299 (1.1)9450 (0.8)0.02
 ≥ 38226 (0.7)1002 (0.8)7224 (0.6)0.02
 Missing1 029 649 (82.7)89 235 (74.4)940 414 (83.6)0.23
Adjusted Diagnostic Group score
 032 505 (2.6)3011 (2.5)29 494 (2.6)0.01
 1–3137 524 (11.0)12 762 (10.6)124 762 (11.1)0.01
 4–6318 091 (25.5)29 369 (24.5)288 722 (25.7)0.03
 7–9371 691 (29.8)34 265 (28.6)337 426 (30.0)0.03
 ≥ 10385 646 (31.0)40 541 (33.8)345 105 (30.7)0.07
Comorbidities
 Vascular diseases15 082 (1.2)1898 (1.6)13 184 (1.2)153.04
 Hypertension44 240 (3.6)3720 (3.1)40 520 (3.6)78.72
 Diabetes18 251 (1.5)2173 (1.8)16 078 (1.4)110.18
 Dyslipidemia4504 (0.4)618 (0.5)3886 (0.4)86.90
 Respiratory diseases8390 (0.7)1740 (1.4)6650 (0.6)1197.55
 Arthritis2547 (0.2)302 (0.2)2245 (0.2)14.53
 Crohn disease/ulcerative colitis2135 (0.2)198 (0.3)1937 (0.2)0.31
 Osteoporosis724 (0.1)138 (0.1)586 (0.05)74.02
 Obesity4646 (0.4)942 (0.8)3704 (0.3)607.13
 Pelvic inflammatory diseases870 (0.1)115 (0.1)755 (0.1)12.87
 Polycystic ovary syndrome126 (0.01)27 (0.02)99 (0.01)20.15
 Attached to family physician
  Yes1 186 316 (95.3)113 722 (94.8)1 072 594 (95.3)0.01
  No59 141 (4.7)6226 (5.2)52 915 (4.7)0.01
  • Note: IQR = interquartile range.

  • * Except where noted otherwise.

  • χ2 test for comorbidities. For other characteristics, we calculated standardized differences through the difference in the mean between the 2 groups divided by an estimate of the standard deviation.