Definitions of Clostridioides difficile infection cohorts based on location of disease association and onset*
| Cohort | Definition |
|---|---|
| ACH-associated/ACH-onset | C. difficile infection was coded as postadmission comorbidity of clinical significance AND patient did not reside in LTCF in 12 wk before admission |
| ACH- or LTCF-associated†/ACH-onset | C. difficile infection was coded as postadmission comorbidity of clinical significance AND patient resided in LTCF in 12 wk before admission |
| LTCF-associated/LTCF-onset | C. difficile infection was coded as most responsible diagnosis or preadmission comorbidity AND patient resided in LTCF with no history of hospital admission in 12 wk before admission |
| LTCF- or ACH-associated†/LTCF-onset | C. difficile infection was coded as most responsible diagnosis or preadmission comorbidity AND patient resided in LTCF in 12 wk before admission AND patient had history of hospital admission during this time |
| Community-associated/community-onset | C. difficile infection was coded as most responsible diagnosis or preadmission comorbidity AND patient neither resided in LTCF nor was admitted to hospital in 12 wk before admission |
| ACH-associated/community-onset | C. difficile infection was coded as most responsible diagnosis or preadmission comorbidity AND patient did not reside in LTCF but was admitted to hospital in 12 wk before admission |
Note: ACH = acute care hospital, LTCF = long-term care facility.
↵* Adapted from reference (18). Reproduced with permission.
↵† Because the case involved a person who resided in an LTCF and was admitted to hospital in the 12 weeks before onset, it was not possible to determine whether the infection was acquired in an ACH or LTCF.