Table 2:

Scenario analyses relating to year of epidemiologic data, discount rate, time horizon and source of vaccine effectiveness

Scenario	Total costs per 1000 pregnant women, $^*		Total QALYs per 1000 pregnant women		Incremental cost of vaccination per QALY gained, $^*^†

	Vaccine	No vaccine	Vaccine	No vaccine
Base case	17 404	4417	73 016.4	73 016.1	44 729

Year

2006	17 579	6339	73 015.4	73 015.0	26 660

2007	17 464	5089	73 017.2	73,016.8	37 024

2008	17 525	5750	73,017.1	73 016.7	30 961

2009	17 437	4766	73 015.7	73 015.4	40 811

2010	17 210	2297	73 016.8	73 016.6	100 348

2011	17 224	2448	73 015.7	73 015.5	93 145

2012	17 691	7551	73 015.6	73 015.1	20 463

2013	17 248	2703	73 016.8	73 016.6	82 554

2014	17 244	2672	73 016.2	73 016.0	83 076

2015	17 415	4533	73 017.6	73 017.3	42 772

Discount rate, %

0	17 413	4521	117 249.1	117 248.7	29 365

3	17 397	4349	50 463.6	50 463.4	59 594

5	17 394	4295	34 738.1	34 737.9	75 872

50-yr time horizon	17 402	4395	60 992.1	60 991.9	54 398

Vaccine effectiveness28 (n = 96)	18 569	4409	73 017.8	73 017.5	55 031

Note: QALY = quality-adjusted life-year.
↵* In 2019 Canadian dollars.
↵† Bolded values represent scenarios under which vaccination during pregnancy would be cost-effective assuming a willingness to pay per QALY gained of $50 000.