Table 3:

Risk of bias assessment

StudySelection biasAscertainment biasCausalityQuality of reporting, description
Is (are) the patient(s) representative of the investigating centre?Was the exposure/ outcome adequately ascertained?Was an alternative cause ruled out?Was there a challenge– rechallenge phenomenon?Was there a dose– response effect?Was follow-up long enough?Was (were) the case(s) described in sufficient detail?
O’Reilly et al. (28)Patient selection method NSYes/yesYesNoNoYesYes
Denkler and Cohen (43)Patient selection method NSYes/yesYesNoNoYesYes
Wong et al. (40)Patient selection method NSYes/yesYesNoNoYesYes
Varughese and Koh (41)Patient selection method NSYes/yesYesNoNoYesYes
Baserga et al. (25)Patient selection method NSYes/yesYesNoNoYesYes
Vasquez et al. (30)Patient selection method NSYes/yesYesNoNoYesYes
Maffei et al. (23)Patient selection method NSYes/yesYesNoNoYesYes
Ancora et al. (39)Patient selection method NSYes/yesYesNoNoYesYes
Mousavi et al. (38)Patient selection method NSNSYesNoNoYesYes
Akingbola et al. (34)Patient selection method NSYes/yesYesYesNoYesYes
Mosalli et al. (35)Patient selection method NSYes/yesYesNoNoYesYes
Kamar et al. (44)Patient selection method NSYes/sesYesNoNoYesYes
Samiee-Zafarghandy et al. (22)Patient selection method NSYes/yesYesNoNoYesYes
Dilli et al. (33)Patient selection method NSYes/yesYesNoNoYesYes
Teo and Shah (31)Patient selection method NSYes/yesYesNoNoYesYes
Parra et al. (29)Patient selection method NSYes/yesYesNoNoYesYes
Vivar del Hoyo et al. (24)Patient selection method NSYes/yesYesNoNoYesYes
Yong et al. (42)YesYes/yesYesNoNoYesYes
Han et al. (37)Patient selection method NSYes/yesYesNoNoYesYes
Isik et al. (36)Patient selection method NSYes/yesYesNoNoYesYes
Mintoft et al. (26)Patient selection method NSYes/yesYesNoNoYesYes
Kuttysankaran et al. (32)Patient selection method NSYes/yesYesNoNoYesYes
Weeraskera et al. (27)Patient selection method NSYes/yesYesNoNoYesYes
  • Note: NS = not stated. Risk of bias was ascertained using the Tool for Evaluating the Methodological Quality of Case Reports and Case Series. (21)