Variation in prevalence and nature of PPI across trial characteristics among those who did and did not report PPI
| Characteristic | No. (%) of responses | |
|---|---|---|
| Reported PPI n = 334 | Reported no PPI n = 333 | |
| Trial population (self-report) | ||
| Children only (< 18 yr) | 71 (55.9) | 56 (44.1) |
| Older adults only (> 65 yr) | 46 (50.0) | 46 (50.0) |
| Neither of the above | 217 (48.4) | 231 (51.6) |
| Country of corresponding author (n = 663)* | ||
| Canada | 13 (31.0) | 29 (69.0) |
| United States | 119 (47.4) | 132 (52.6) |
| United Kingdom | 90 (79.6) | 23 (20.4) |
| Non-UK Europe | 73 (42.7) | 98 (57.3) |
| Australia or New Zealand | 42 (47.7) | 46 (52.3) |
| South Africa | 1 (16.7) | 5 (83.3) |
| Other | 5 (71.4) | 2 (28.6) |
| Unit of randomization (n = 665)† | ||
| Individual | 122 (43.9) | 156 (56.1) |
| Cluster | 211 (54.5) | 176 (45.5) |
| Study manuscript used the word “pragmatic” in reference to the trial (n = 665)† | ||
| Yes | 124 (60.8) | 80 (39.2) |
| No | 209 (45.3) | 252 (54.7) |
| Year of publication (n = 665)† | ||
| 2014 | 39 (46.4) | 45 (53.6) |
| 2015 | 48 (42.1) | 66 (57.9) |
| 2016 | 52 (47.7) | 57 (52.3) |
| 2017 | 73 (51.4) | 69 (48.6) |
| 2018 | 92 (56.1) | 72 (43.9) |
| 2019 | 29 (55.8) | 23 (44.2) |