Influence of omeprazol on the antiplatelet action of clopidogrel associated to aspirin

MeSH terms

• Aged
• Angioplasty / adverse effects
• Angioplasty / methods
• Aryl Hydrocarbon Hydroxylases / antagonists & inhibitors
• Aryl Hydrocarbon Hydroxylases / genetics
• Aryl Hydrocarbon Hydroxylases / metabolism
• Aspirin / antagonists & inhibitors*
• Aspirin / pharmacology
• Cell Adhesion Molecules / metabolism*
• Clopidogrel
• Coronary Disease / complications
• Coronary Disease / genetics
• Coronary Disease / metabolism*
• Coronary Disease / surgery
• Cytochrome P-450 CYP2C19
• Drug Antagonism
• Enzyme Inhibitors / pharmacology
• Female
• Humans
• Male
• Microfilament Proteins / metabolism*
• Mixed Function Oxygenases / antagonists & inhibitors
• Mixed Function Oxygenases / genetics
• Mixed Function Oxygenases / metabolism
• Omeprazole / antagonists & inhibitors*
• Omeprazole / pharmacology
• Phosphoproteins / metabolism*
• Phosphorylation / drug effects
• Platelet Activation / drug effects*
• Platelet Activation / genetics
• Platelet Aggregation Inhibitors / pharmacology
• Platelet Function Tests / methods
• Polymorphism, Single Nucleotide
• Protein Processing, Post-Translational / drug effects
• Thrombosis / etiology
• Thrombosis / genetics
• Thrombosis / metabolism
• Ticlopidine / analogs & derivatives*
• Ticlopidine / antagonists & inhibitors
• Ticlopidine / pharmacology