Association between peanut allergy and asthma morbidity

J Pediatr. 2010 May;156(5):777-81, 781.e1. doi: 10.1016/j.jpeds.2009.11.080. Epub 2010 Feb 12.

Abstract

Objective: To evaluate the relationship between peanut allergy and asthma morbidity in school-age children.

Study design: The study involved a medical chart review to assess the association of peanut allergy with asthma morbidity in children beyond age 3 years. Peanut allergy was assessed by specific and validated criteria. A Poisson regression model was used to compare the frequency of systemic steroid use and of hospitalization for asthma beyond age 3 years in children with asthma with and without peanut allergy.

Results: Children with peanut allergy had a 2.32-times greater rate of hospitalization (P = .03) and a 1.59-times greater rate of systemic steroid use (P <.001) after controlling for covariates.

Conclusions: Peanut allergy serves as an early marker for asthma morbidity. Early prevention and intervention can improve quality of care.

MeSH terms

  • Administration, Inhalation
  • Adolescent
  • Asthma / drug therapy
  • Asthma / etiology*
  • Asthma / therapy
  • Child
  • Child, Preschool
  • Female
  • Glucocorticoids / administration & dosage
  • Hospitalization
  • Humans
  • Immunoglobulin E / blood
  • Male
  • Peanut Hypersensitivity / complications*
  • Peanut Hypersensitivity / diagnosis
  • Skin Tests

Substances

  • Glucocorticoids
  • Immunoglobulin E