User profiles for David N. Juurlink
David JuurlinkClinical Pharmacology and Toxicology, University of Toronto Verified email at ices.on.ca Cited by 34483 |
[HTML][HTML] Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study
DN Juurlink, MM Mamdani, DS Lee… - … England Journal of …, 2004 - Mass Medical Soc
Background The Randomized Aldactone Evaluation Study (RALES) demonstrated that
spironolactone significantly improves outcomes in patients with severe heart failure. Use of …
spironolactone significantly improves outcomes in patients with severe heart failure. Use of …
[HTML][HTML] A population-based study of the drug interaction between proton pump inhibitors and clopidogrel
Background: Most proton pump inhibitors inhibit the bioactivation of clopidogrel to its active
metabolite. The clinical significance of this drug interaction is unknown. Methods: We …
metabolite. The clinical significance of this drug interaction is unknown. Methods: We …
Unintended medication discrepancies at the time of hospital admission
…, V Tam, S Shadowitz, DN Juurlink… - Archives of internal …, 2005 - jamanetwork.com
Background Prior studies suggest that unintended medication discrepancies that represent
errors are common at the time of hospital admission. These errors are particularly worthy of …
errors are common at the time of hospital admission. These errors are particularly worthy of …
Drug-drug interactions among elderly patients hospitalized for drug toxicity
DN Juurlink, M Mamdani, A Kopp, A Laupacis… - Jama, 2003 - jamanetwork.com
ContextDrug-drug interactions are a preventable cause of morbidity and mortality, yet their
consequences in the community are not well characterized.ObjectiveTo determine whether …
consequences in the community are not well characterized.ObjectiveTo determine whether …
Long-term analgesic use after low-risk surgery: a retrospective cohort study
…, H Zheng, MM Mamdani, DN Juurlink… - Archives of internal …, 2012 - jamanetwork.com
Background This study evaluated the risk of long-term analgesic use after low-risk surgery
in older adults not previously prescribed analgesics. Methods We conducted a retrospective …
in older adults not previously prescribed analgesics. Methods We conducted a retrospective …
Responding to the opioid crisis in North America and beyond: recommendations of the Stanford–Lancet Commission
The Stanford–Lancet Commission on the North American Opioid Crisis was formed in response
to soaring opioid-related morbidity and mortality in the USA and Canada over the past …
to soaring opioid-related morbidity and mortality in the USA and Canada over the past …
Medical illness and the risk of suicide in the elderly
DN Juurlink, N Herrmann, JP Szalai… - Archives of internal …, 2004 - jamanetwork.com
Background Suicide is a leading cause of death, and rates are especially high among the
elderly. Medical illnesses may predispose to suicide, but few controlled studies have …
elderly. Medical illnesses may predispose to suicide, but few controlled studies have …
Opioid dose and drug-related mortality in patients with nonmalignant pain
…, IA Dhalla, JM Paterson, DN Juurlink - Archives of internal …, 2011 - jamanetwork.com
Background Opioids are widely prescribed for chronic nonmalignant pain, often at doses
exceeding those recommended in clinical practice guidelines. However, the risk-benefit ratio of …
exceeding those recommended in clinical practice guidelines. However, the risk-benefit ratio of …
[HTML][HTML] Guideline for opioid therapy and chronic noncancer pain
JW Busse, S Craigie, DN Juurlink, DN Buckley, L Wang… - Cmaj, 2017 - Can Med Assoc
Methods In developing this guideline, the steering committee followed standards for trustworthy
guidelines. 15 We included innovative approaches for key standards such as patient …
guidelines. 15 We included innovative approaches for key standards such as patient …
Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort study
CM Kelly, DN Juurlink, T Gomes, M Duong-Hua… - Bmj, 2010 - bmj.com
Objective To characterise whether some selective serotonin reuptake inhibitor (SSRI)
antidepressants reduce tamoxifen’s effectiveness by inhibiting its bioactivation by cytochrome …
antidepressants reduce tamoxifen’s effectiveness by inhibiting its bioactivation by cytochrome …