Although pain is experienced at all ages, there is uncertainty about the pattern of its
occurrence in older people. We have investigated the prevalence of three aspects of self-reported …

Objective To determine whether there is sufficient evidence to conclude that exercise
interventions are more effective than no exercise control and to compare the effectiveness of …

Objective Studies of previous cohorts have demonstrated an association between a status
of overweight/obesity and the presence of knee and hand osteoarthritis (OA). However, no …

Background Estimating the future course of musculoskeletal pain is an important consideration
in the primary care consultation for patients and healthcare professionals. Studies of …

Background There is growing evidence that sleep duration and quality may be associated
with cardiovascular harm and mortality. Methods and Results We conducted a systematic …

A systematic review and meta-analysis of population-based epidemiological studies was
undertaken to determine the prevalence of foot and ankle pain in middle and old age. …

OBJECTIVE: There is no consensus on the best method to determine the minimal important
change (MIC) of patient-reported outcomes. Recent publications recommend the use of …

Background Patellofemoral osteoarthritis (PFOA) is a common form of knee OA in middle
and older age, but its relation to PF disorders and symptoms earlier in life is unclear. Our aim …

… George Peat, … Correspondence to George Peat, School of Healthcare, University of
Leeds, Leeds LS2 9JT, UK; hcgwp{at}leeds.ac.uk …

Background Diagnosis is the traditional basis for decision-making in clinical practice. Evidence
is often lacking about future benefits and harms of these decisions for patients diagnosed …