User profiles for Adrienne Chan

Adrienne K. Chan

University of Toronto
Verified email at sunnybrook.ca
Cited by 7422

[HTML][HTML] Identification of severe acute respiratory syndrome in Canada

…, R Draker, D Adachi, M Ayers, AK Chan… - … England Journal of …, 2003 - Mass Medical Soc
Background Severe acute respiratory syndrome (SARS) is a condition of unknown cause
that has recently been recognized in patients in Asia, North America, and Europe. This report …

[HTML][HTML] Antifungal combinations for treatment of cryptococcal meningitis in Africa

…, E Temfack, S Lakhi, S Lesikari, AK Chan… - … England Journal of …, 2018 - Mass Medical Soc
Background Cryptococcal meningitis accounts for more than 100,000 human immunodeficiency
virus (HIV)–related deaths per year. We tested two treatment strategies that could be …

Association between nursing home crowding and COVID-19 infection and mortality in Ontario, Canada

KA Brown, A Jones, N Daneman, AK Chan… - JAMA internal …, 2021 - jamanetwork.com
Importance Nursing home residents have been disproportionately affected by coronavirus
disease 2019 (COVID-19). Prevention recommendations emphasize frequent testing of health …

Enhanced CTL responses mediated by plasmid DNA immunogens encoding costimulatory molecules and cytokines.

A Iwasaki, BJ Stiernholm, AK Chan… - … (Baltimore, Md.: 1950 …, 1997 - journals.aai.org
In the course of examining epitope-specific CTL responses to intramuscular plasmid DNA
immunization with influenza nucleoprotein (NP)-expressing vectors, a nonimmunogenic …

[HTML][HTML] Peginterferon lambda for the treatment of outpatients with COVID-19: a phase 2, placebo-controlled randomised trial

…, J Powis, J McCready, DHS Tan, T Chan… - The Lancet …, 2021 - thelancet.com
Background To date, only monoclonal antibodies have been shown to be effective for
outpatients with COVID-19. Interferon lambda-1 is a type III interferon involved in innate antiviral …

[HTML][HTML] Adjunctive dexamethasone in HIV-associated cryptococcal meningitis

…, W Supphamongkholchaikul, AK Chan… - … England Journal of …, 2016 - Mass Medical Soc
Background Cryptococcal meningitis associated with human immunodeficiency virus (HIV)
infection causes more than 600,000 deaths each year worldwide. Treatment has changed …

[HTML][HTML] Illness in intensive care staff after brief exposure to severe acute respiratory syndrome

DC Scales, K Green, AK Chan… - Emerging infectious …, 2003 - ncbi.nlm.nih.gov
Methods After research ethics board approval and informed consent, two researchers used
a structured questionnaire to interview quarantined healthcare workers. The questionnaire …

[HTML][HTML] Early clinical sequelae of Ebola virus disease in Sierra Leone: a cross-sectional study

…, J Shantha, V Wolfman, S Yeh, AK Chan… - The Lancet Infectious …, 2016 - thelancet.com
Background Limited data are available on the prevalence and predictors of clinical sequelae
in survivors of Ebola virus disease (EVD). The EVD Survivor Clinic in Port Loko, Sierra …

[HTML][HTML] Global, regional, and national trends in opioid analgesic consumption from 2015 to 2019: a longitudinal study

…, AYL Chan, R Brauer, CSL Chui, EW Chan… - The Lancet Public …, 2022 - thelancet.com
Background Previous studies have reported an extremely unbalanced global access to opioid
analgesics. We aimed to determine contemporary trends and patterns of opioid analgesic …

Inhaled and intranasal ciclesonide for the treatment of covid-19 in adult outpatients: CONTAIN phase II randomised controlled trial

N Ezer, S Belga, N Daneman, A Chan, BM Smith… - Bmj, 2021 - bmj.com
Objective To determine if inhaled and intranasal ciclesonide are superior to placebo at
decreasing respiratory symptoms in adult outpatients with covid-19. Design Randomised, double …