User profiles for Alan Tinmouth

Alan Tinmouth

Associate Professor, University of Ottawa. Scientist, Ottawa Hospital Research Institute
Verified email at toh.ca
Cited by 13167

Red blood cell transfusion: a clinical practice guideline from the AABB

…, BJ Grossman, S Kleinman, AT Tinmouth… - Annals of internal …, 2012 - acpjournals.org
Description: Although approximately 85 million units of red blood cells (RBCs) are transfused
annually worldwide, transfusion practices vary widely. The AABB (formerly, the American …

Platelet transfusion: a clinical practice guideline from the AABB

…, T Gernsheimer, S Kleinman, AT Tinmouth… - Annals of internal …, 2015 - acpjournals.org
Background: The AABB (formerly, the American Association of Blood Banks) developed this
guideline on appropriate use of platelet transfusion in adult patients. Methods: These …

Clinical consequences of red cell storage in the critically ill

A Tinmouth, D Fergusson, IC Yee, PC Hébert… - …, 2006 - Wiley Online Library
Red cell (RBC) transfusions are a potentially life‐saving therapy employed during the care
of many critically ill patients to replace losses in hemoglobin to maintain oxygen delivery to …

[HTML][HTML] Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

…, E Jamula, R Cook, NM Heddle, A Tinmouth… - Nature medicine, 2021 - nature.com
The efficacy of convalescent plasma for coronavirus disease 2019 (COVID-19) is unclear.
Although most randomized controlled trials have shown negative results, uncontrolled studies …

[HTML][HTML] Age of transfused blood in critically ill adults

…, PC Hébert, DA Fergusson, A Tinmouth… - … England Journal of …, 2015 - Mass Medical Soc
Background Fresh red cells may improve outcomes in critically ill patients by enhancing
oxygen delivery while minimizing the risks of toxic effects from cellular changes and the …

Transfusion reactions: prevention, diagnosis, and treatment

…, TO Apelseth, M Popovsky, SJ Stanworth, A Tinmouth… - The Lancet, 2016 - thelancet.com
Blood transfusion is one of the most common procedures in patients in hospital so it is
imperative that clinicians are knowledgeable about appropriate blood product administration, as …

Effect of fresh red blood cell transfusions on clinical outcomes in premature, very low-birth-weight infants: the ARIPI randomized trial

…, JA Smyth, K Sankaran, A Tinmouth… - Jama, 2012 - jamanetwork.com
Context Even though red blood cells (RBCs) are lifesaving in neonatal intensive care,
transfusing older RBCs may result in higher rates of organ dysfunction, nosocomial infection, and …

Evidence‐based selection of theories for designing behaviour change interventions: Using methods based on theoretical construct domains to understand clinicians' …

…, JM Grimshaw, C Hyde, A Tinmouth… - British journal of …, 2009 - Wiley Online Library
Background Many theories of behaviour are potentially relevant to predictive and intervention
studies but most studies investigate a narrow range of theories. Michie et al. (2005) agreed …

[HTML][HTML] Effect of donor sex on recipient mortality in transfusion

M Chassé, DA Fergusson, A Tinmouth… - … England Journal of …, 2023 - Mass Medical Soc
Background Conflicting observational evidence exists regarding the association between
the sex of red-cell donors and mortality among transfusion recipients. Evidence to inform …

[HTML][HTML] Continuous multi-parameter heart rate variability analysis heralds onset of sepsis in adults

…, FM Shamji, P Hebert, D Fergusson, A Tinmouth… - PloS one, 2009 - journals.plos.org
Background Early diagnosis of sepsis enables timely resuscitation and antibiotics and
prevents subsequent morbidity and mortality. Clinical approaches relying on point-in-time …