User profiles for Alex Choi

Alex Choi

Staff Research Associate, UCSF
Verified email at ucsf.edu
Cited by 789

Applications of luminescent inorganic and organometallic transition metal complexes as biomolecular and cellular probes

KKW Lo, AWT Choi, WHT Law - Dalton Transactions, 2012 - pubs.rsc.org
The rich photophysical properties of luminescent inorganic and organometallic transition metal
complexes, such as their intense, long-lived, and environment-sensitive emission, render …

Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy

…, L Epling, Q Li, L Duan, ALM Choi… - The Journal of …, 2010 - academic.oup.com
Background. The gut is a major reservoir for human immunodeficiency virus (HIV) in patients
receiving antiretroviral therapy (ART). We hypothesized that distinct immune environments …

[HTML][HTML] Pathogenesis underlying neurological manifestations of long COVID syndrome and potential therapeutics

…, L Premraj, K Wildi, G Li Bassi, CA Pardo, A Choi… - Cells, 2023 - mdpi.com
The development of long-term symptoms of coronavirus disease 2019 (COVID-19) more
than four weeks after primary infection, termed “long COVID” or post-acute sequela of COVID-…

[HTML][HTML] Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain

CN Serhan, J Dalli, S Karamnov, A Choi… - The FASEB …, 2012 - ncbi.nlm.nih.gov
Self-resolving inflammatory exudates and lipid mediator metabolomics recently uncovered
a new family of potent anti-inflammatory and proresolving mediators biosynthesized by …

[HTML][HTML] The cinnamyl alcohol dehydrogenase gene family in Populus: phylogeny, organization, and expression

A Barakat, A Bagniewska-Zadworna, A Choi… - BMC plant biology, 2009 - Springer
Background Lignin is a phenolic heteropolymer in secondary cell walls that plays a major
role in the development of plants and their defense against pathogens. The biosynthesis of …

[HTML][HTML] Modification of messenger RNA by 2′-O-methylation regulates gene expression in vivo

…, S Vangaveti, O Ilkayeva, H Abou Assi, AK Choi… - Nature …, 2019 - nature.com
Epitranscriptomic modifications of mRNA are important regulators of gene expression. While
internal 2′-O-methylation (Nm) has been discovered on mRNA, questions remain about its …

KRASG12C inhibition produces a driver-limited state revealing collateral dependencies

…, YC Hwang, CH Yogodzinski, AR Shkedi, ALM Choi… - Science …, 2019 - science.org
Inhibitors targeting KRAS G12C , a mutant form of the guanosine triphosphatase (GTPase)
KRAS, are a promising new class of oncogene-specific therapeutics for the treatment of …

Dual-emissive cyclometalated iridium (III) polypyridine complexes as ratiometric biological probes and organelle-selective bioimaging reagents

KY Zhang, HW Liu, MC Tang, AWT Choi, N Zhu… - Inorganic …, 2015 - ACS Publications
In this Article, we present a series of cyclometalated iridium(III) polypyridine complexes of the
formula [Ir(N^C) 2 (N^N)](PF 6 ) that showed dual emission under ambient conditions. The …

[PDF][PDF] An Mtb-human protein-protein interaction map identifies a switch between host antiviral and antibacterial responses

…, SL Bell, K Geiger, G Golovkine, X Du, A Choi… - Molecular cell, 2018 - cell.com
Although macrophages are armed with potent antibacterial functions, Mycobacterium
tuberculosis (Mtb) replicates inside these innate immune cells. Determinants of macrophage …

[HTML][HTML] Inflammasomes: molecular regulation and implications for metabolic and cognitive diseases

AJS Choi, SW Ryter - Molecules and cells, 2014 - Elsevier
Inflammasomes are specialized signaling platforms critical for the regulation of innate immune
and inflammatory responses. Various NLR family members (ie, NLRP1, NLRP3, and IPAF…