User profiles for Alex Haines

Alexander Haines

CADTH
Verified email at cadth.ca
Cited by 480

Identification, assessment, and management of overweight and obesity: summary of updated NICE guidance

H Stegenga, A Haines, K Jones, J Wilding - Bmj, 2014 - bmj.com
… Heather Stegenga systematic reviewer1, Alexander Haines health economist2, Katie
Jones senior … Haines@rcplondon.ac.uk … The members of the Guideline Development …

The UDP-glycosyltransferase (UGT) superfamily: new members, new functions, and novel paradigms

…, SN Mubarokah, AZ Haines… - Physiological …, 2019 - journals.physiology.org
UDP-glycosyltransferases (UGTs) catalyze the covalent addition of sugars to a broad range
of lipophilic molecules. This biotransformation plays a critical role in elimination of a broad …

[HTML][HTML] An economic evaluation of vector control in the age of a dengue vaccine

C Fitzpatrick, A Haines, M Bangert… - PLoS neglected …, 2017 - journals.plos.org
Introduction Dengue is a rapidly emerging vector-borne Neglected Tropical Disease, with a
30-fold increase in the number of cases reported since 1960. The economic cost of the …

The UGTome: The expanding diversity of UDP glycosyltransferases and its impact on small molecule metabolism

DG Hu, PC Nair, AZ Haines, RA McKinnon… - Pharmacology & …, 2019 - Elsevier
The UDP glycosyltransferase (UGT) superfamily of enzymes is responsible for the
metabolism and clearance of thousands of lipophilic chemicals including drugs, toxins and …

[HTML][HTML] Antiviral treatment for treatment-naïve chronic hepatitis B: systematic review and network meta-analysis of randomized controlled trials

…, P Pechivanoglou, J Wong, JM Bielecki, A Haines… - Systematic …, 2019 - Springer
Background Chronic hepatitis B (CHB) infection poses a significant burden to public health
worldwide. Most cases are clinically silent until late in the disease course. The main goal of …

Health care costs associated with chronic hepatitis C virus infection in Ontario, Canada: a retrospective cohort study

WWL Wong, A Haines, KE Bremner, Z Yao… - … Open Access Journal, 2021 - cmajopen.ca
Background: High-quality estimates of health care costs are required to understand the
burden of illness and to inform economic models. We estimated the costs associated with …

Estimating chronic hepatitis C prevalence in British Columbia and Ontario, Canada, using population‐based cohort studies

A Hamadeh, A Haines, Z Feng, HH Thein… - Journal of Viral …, 2020 - Wiley Online Library
Patients identified as having chronic hepatitis C (CHC) infection can be effectively and rapidly
treated using direct‐acting antiviral agents. However, there remains a substantial burden …

[HTML][HTML] A province-by-province cost-effectiveness analysis and budget impact analysis of one-time birth cohort screening of hepatitis C virus (HCV) infection in …

WWL Wong, A Haines, J Wong, A Hamadeh… - Scientific Reports, 2023 - nature.com
Managing chronic hepatitis C is challenging, as the majority of those infected are
asymptomatic. Therefore, to ensure treatments are administered before the onset of severe …

Can we afford not to screen and treat hepatitis C virus infection in Canada?

WWL Wong, A Haines… - Canadian Liver …, 2018 - canlivj.utpjournals.press
Background Screening for hepatitis C virus (HCV) followed by direct-acting antiviral (DAA)
treatment in individuals born between 1945 and 1964 has been shown to be both effective …

Exploring perceived barriers for advancement to leadership positions in healthcare: a thematic synthesis of women's experiences

AC Haines, E McKeown - Journal of Health Organization and …, 2023 - emerald.com
Alexandra Claire Haines (School of Health Sciences, City University of London, London,
UK) … Haines, AC and McKeown, E. (2023), "Exploring perceived barriers for advancement …