Gut homing receptors on CD8 T cells are retinoic acid dependent and not maintained by liver dendritic or stellate cells

…, EJ Villablanca, SM Curbishley, AI Aspinall… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Lymphocytes primed by intestinal dendritic cells (DC) express the
gut-homing receptors CCR9 and α4β7, which recognize CCL25 and mucosal addressin cell-…

Lack of chemokine receptor CCR5 promotes murine fulminant liver failure by preventing the apoptosis of activated CD1d-restricted NKT cells

MN Ajuebor, AI Aspinall, F Zhou, T Le… - The Journal of …, 2005 - journals.aai.org
Fulminant liver failure (FLF) consists of a cascade of events beginning with a presumed
uncontrolled systemic activation of the immune system. The etiology of FLF remains undefined. …

Real-world treatment of hepatitis C with second-generation direct-acting antivirals: initial results from a multicentre Canadian retrospective cohort of diverse patients

AI Aspinall, AA Shaheen, GS Kochaksaraei… - … Open Access Journal, 2018 - cmajopen.ca
… Abdel Shaheen and Alex Aspinall interpreted the data. Alex Aspinall drafted the manuscript,
and Alex Aspinall, Abdel Shaheen and Carla Coffin revised it critically for important …

Concurrence of primary biliary cirrhosis and antiphospholipid antibody syndrome

AI Aspinall, SS Lee - Official journal of the American College of …, 2004 - journals.lww.com
TO THE EDITOR: Colombel et al. recently published an interesting paper showing that
infliximab is beneficial in the treatment of patients with an ileo-anal pouch anastomosis (IPAA) …

[HTML][HTML] Asymptotic growth of whale sharks suggests sex-specific life-history strategies

…, ADM Dove, MJ Birt, A Aspinall… - Frontiers in Marine …, 2020 - frontiersin.org
Age and growth data are central to management or conservation strategies for any species.
Circumstantial evidence suggests that male whale sharks (Rhincodon typus) grow to …

A Phase II trial of second‐line axitinib following prior antiangiogenic therapy in advanced hepatocellular carcinoma

MG McNamara, LW Le, AM Horgan, A Aspinall… - Cancer, 2015 - Wiley Online Library
BACKGROUND Second‐line treatment options in advanced hepatocellular carcinoma (HCC)
are limited. Axitinib, a selective potent tyrosine kinase inhibitor (TKI) of vascular …

Membrane fluidity increases during apoptosis of sheep ileal Peyer's patch B cells

D Jourd'heuil, A Aspinall, JD Reynolds… - Canadian journal of …, 1996 - cdnsciencepub.com
To investigate specific plasma membrane structural changes associated with apoptosis,
whole cells and purified plasma membranes of apoptotic B cells from the ileal Peyer’s patch of …

TEM Classification of Aortic Dissection—The Evolving Scoring System: A Literature Review

…, M Abdelghaffar, S Babiker, A Aspinall… - Heart, Lung and …, 2023 - Elsevier
Aortic dissection is an acute presentation that, if unnoticed, poses a significant risk to life.
Anatomically, it is defined as a tear in the intimal layer of the aorta, but management differs …

Cardiac arrhythmia and sudden death in relation to COVID-19

I Ahmed, A Aspinall, RSK Patel, J Merza - COVID-19's Consequences on …, 2024 - Elsevier
Cardiac arrhythmias are a common manifestation described in patients with SARS-CoV-2 (COVID-19)
infection. Symptoms can vary from palpitations to life-threatening arrhythmias. …

A phase II trial of second-line axitinib following prior antiangiogenic therapy in advanced hepatocellular carcinoma (HCC).

MG McNamara, LW Le, AM Horgan, A Aspinall… - 2014 - ascopubs.org
4092 Background: Second line treatment options in advanced HCC are limited. Axitinib, a
selective tyrosine kinase inhibitor (TKI) of VEGFRs 1, 2, 3, merits exploration in HCC. Methods: …