Wildlife reservoirs of broad-host-range viruses have the potential to enable evolution of viral
variants that can emerge to infect humans. In North America, there is phylogenomic …

We measured the prevalence and temporal trends of pulmonary nontuberculous mycobacterial
disease among residents of Ontario, Canada, during 1998–2010. Five-year prevalence …

Inhaled corticosteroid (ICS) use is associated with an increased risk of pneumonia. This
study was performed to determine if ICS use is associated with an increased risk of …

Rationale Anti-tumour necrosis factor (TNF) agents and other anti-rheumatic medications
increase the risk of TB in rheumatoid arthritis (RA). Whether they increase the risk of infections …

Background: A resurgence of pertussis cases among both vaccinated and unvaccinated
people raises questions about vaccine effectiveness over time. Our objective was to study the …

Wildlife reservoirs of SARS-CoV-2 can lead to viral adaptation and spillback from wildlife to
humans ( Oude Munnink et al., 2021 ). In North America, there is evidence of spillover of …

Bloodstream infections (BSIs) represent a substantial mortality risk, yet most studies are limited
to select pathogens or populations. The aim of this study was to describe the population-…

The local epidemiology of antimicrobial susceptibility patterns in anaerobic bacteria is
important in guiding the empiric treatment of infections. However, susceptibility data are very …

Survival implications of nontuberculous mycobacterial pulmonary disease (NTM-PD) and
NTM pulmonary isolation without disease (NTM-PI) are unclear. To study deaths associated …

An outbreak of type emm59 invasive group A Streptococcus (iGAS) disease was declared in
2008 in Thunder Bay District, Northwestern Ontario, 2 years after a countrywide emm59 …