Cohort profile update: the Swiss HIV cohort study (SHCS)
AU Scherrer, A Traytel, DL Braun… - International journal …, 2022 - academic.oup.com
The Swiss HIV Cohort Study (SHCS) provides a unique research platform for clinical,
translational, epidemiological, social and basic research. The SHCS was established in 1988. It is …
translational, epidemiological, social and basic research. The SHCS was established in 1988. It is …
[HTML][HTML] Profound depletion of HIV-1 transcription in patients initiating antiretroviral therapy during acute infection
…, S Gianella, V von Wyl, KJ Metzner, AU Scherrer… - PloS one, 2010 - journals.plos.org
Background Although combination antiretroviral therapy (cART) initiated in the acute phase
of HIV-1 infection may prevent expansion of the latent reservoir, its benefits remain …
of HIV-1 infection may prevent expansion of the latent reservoir, its benefits remain …
Characterization of human immunodeficiency virus type 1 (HIV-1) diversity and tropism in 145 patients with primary HIV-1 infection
P Rieder, B Joos, AU Scherrer, H Kuster… - Clinical infectious …, 2011 - academic.oup.com
… Nonparametric tests were used for group comparison (Mann-Whitney U test). Multiple linear
regression was used to analyze the association of viral diversity with viral and host baseline …
regression was used to analyze the association of viral diversity with viral and host baseline …
[HTML][HTML] Persistence of transmitted HIV-1 drug resistance mutations associated with fitness costs and viral genetic backgrounds
…, S Yerly, T Klimkait, V Aubert, AU Scherrer… - PLoS …, 2015 - journals.plos.org
Transmission of drug-resistant pathogens presents an almost-universal challenge for
fighting infectious diseases. Transmitted drug resistance mutations (TDRM) can persist in the …
fighting infectious diseases. Transmitted drug resistance mutations (TDRM) can persist in the …
Assessing the paradox between transmitted and acquired HIV type 1 drug resistance mutations in the Swiss HIV Cohort Study from 1998 to 2012
WL Yang, R Kouyos, AU Scherrer, J Böni… - The Journal of …, 2015 - academic.oup.com
Background. Transmitted human immunodeficiency virus type 1 (HIV) drug resistance (TDR)
mutations are transmitted from nonresponding patients (defined as patients with no initial …
mutations are transmitted from nonresponding patients (defined as patients with no initial …
Incidence of hepatitis C in HIV positive and negative men who have sex with men 2000–2016: a systematic review and meta-analysis
V Ghisla, AU Scherrer, D Nicca, DL Braun, JS Fehr - Infection, 2017 - Springer
Background There is a need for systematic reviews and meta-analyses to synthesize the
epidemiology, and the riskfactors for hepatitis C virus (HCV) among HIV-coinfected and HIV …
epidemiology, and the riskfactors for hepatitis C virus (HCV) among HIV-coinfected and HIV …
Emergence of acquired HIV-1 drug resistance almost stopped in Switzerland: a 15-year prospective cohort analysis
AU Scherrer, V von Wyl, WL Yang… - Clinical infectious …, 2016 - academic.oup.com
Background. Drug resistance is a major barrier to successful antiretroviral treatment (ART).
Therefore, it is important to monitor time trends at a population level. Methods. We included …
Therefore, it is important to monitor time trends at a population level. Methods. We included …
[HTML][HTML] Quantifying the fitness cost of HIV-1 drug resistance mutations through phylodynamics
…, R Kouyos, G Shirreff, J Pečerska, AU Scherrer… - PLoS …, 2018 - journals.plos.org
Drug resistant HIV is a major threat to the long-term efficacy of antiretroviral treatment. Around
10% of ART-naïve patients in Europe are infected with drug-resistant HIV type 1. Hence it …
10% of ART-naïve patients in Europe are infected with drug-resistant HIV type 1. Hence it …
[HTML][HTML] Factors associated with syphilis incidence in the HIV-infected in the era of highly active antiretrovirals
After several years of steady decline, syphilis is reemerging globally as a public health
hazard, especially among people living with human immunodeficiency virus (HIV). Syphilis …
hazard, especially among people living with human immunodeficiency virus (HIV). Syphilis …
[HTML][HTML] Tracing HIV-1 strains that imprint broadly neutralizing antibody responses
…, T Liechti, N Friedrich, DL Braun, AU Scherrer… - Nature, 2018 - nature.com
Understanding the determinants of broadly neutralizing antibody (bNAb) evolution is crucial
for the development of bNAb-based HIV vaccines 1 . Despite emerging information on …
for the development of bNAb-based HIV vaccines 1 . Despite emerging information on …
