User profiles for Alison Sinclair
 | ALISON J SINCLAIRUniversity of Sussex Verified email at sussex.ac.uk Cited by 4924 |
Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro.
…, H Inouye, LK Duffy, A Sinclair… - Proceedings of the …, 1987 - National Acad Sciences
Progressive amyloid deposition in senile plaques and cortical blood vessels may play a
central role in the pathogenesis of Alzheimer disease. We have used x-ray diffraction and …
central role in the pathogenesis of Alzheimer disease. We have used x-ray diffraction and …
EBNA‐2 and EBNA‐LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein‐Barr virus.
AJ Sinclair, I Palmero, G Peters, PJ Farrell - The EMBO journal, 1994 - embopress.org
Epstein‐Barr virus (EBV) is unusual among DNA tumour viruses in that the virus particle is
able to infect and immortalize resting cells with very high efficiency. Mutation of the viral …
able to infect and immortalize resting cells with very high efficiency. Mutation of the viral …
Systematic review and meta-analysis of a urine-based pneumococcal antigen test for diagnosis of community-acquired pneumonia caused by Streptococcus …
A Sinclair, X Xie, M Teltscher… - Journal of clinical …, 2013 - Am Soc Microbiol
Standard culture methods for diagnosis of Streptococcus pneumoniae pneumonia take at
least 24 h. The BinaxNOW urine-based test for S. pneumoniae (BinaxNOW-SP) takes only 15 …
least 24 h. The BinaxNOW urine-based test for S. pneumoniae (BinaxNOW-SP) takes only 15 …
Bioimpedance analysis for the characterization of breast cancer cells in suspension
The bioimpedance spectroscopy (BIS) technique is potentially a useful tool to differentiate
malignancy based on the variation of electrical properties presented by different tissues and …
malignancy based on the variation of electrical properties presented by different tissues and …
Peroxule extension over ER‐defined paths constitutes a rapid subcellular response to hydroxyl stress
AM Sinclair, CP Trobacher, N Mathur… - The Plant …, 2009 - Wiley Online Library
Plants survive against myriad environmental odds while remaining rooted to a single spot.
The time scale over which plant cells can respond to environmental cues is seldom …
The time scale over which plant cells can respond to environmental cues is seldom …
[HTML][HTML] Induction of p16INK4a Is the Major Barrier to Proliferation when Epstein-Barr Virus (EBV) Transforms Primary B Cells into Lymphoblastoid Cell Lines
L Skalska, RE White, GA Parker, AJ Sinclair… - PLoS …, 2013 - journals.plos.org
To explore the role of p16 INK4a as an intrinsic barrier to B cell transformation by EBV, we
transformed primary B cells from an individual homozygous for a deletion in the CDKN2A …
transformed primary B cells from an individual homozygous for a deletion in the CDKN2A …
Contributions of dangling end stacking and terminal base-pair formation to the stabilities of XGGCCp, XCCGGp, XGGCCYp, and XCCGGYp helixes
SM Freier, D Alkema, A Sinclair, T Neilson… - Biochemistry, 1985 - ACS Publications
Materials and Methods Oligonucleotide Synthesis. AGGC, CGGC, UGG, GCCG, and UCCG
were synthesized chemically by using phospho-triester proceduresand were characterized …
were synthesized chemically by using phospho-triester proceduresand were characterized …
bZIP proteins of human gammaherpesviruses
AJ Sinclair - Journal of General Virology, 2003 - microbiologyresearch.org
The human gammaherpesviruses Epstein–Barr virus (EBV) and Kaposi's sarcoma-associated
herpesvirus (KSHV) both infect lymphoid and epithelial cells and both are implicated in …
herpesvirus (KSHV) both infect lymphoid and epithelial cells and both are implicated in …
Preoperative axillary ultrasound and fine-needle aspiration biopsy in the diagnosis of axillary metastases in patients with breast cancer: predictors of accuracy and …
Background The utility of axillary lymph node dissection after sentinel lymph node biopsy has
been called into question. We sought to determine the sensitivity, specificity, and accuracy …
been called into question. We sought to determine the sensitivity, specificity, and accuracy …
Pathways of activation of the Epstein-Barr virus productive cycle
AJ Sinclair, M Brimmell, F Shanahan… - Journal of virology, 1991 - Am Soc Microbiol
The promoter for the 2.8-kb RNA of Epstein-Barr virus encoding BZLF1 and BRLF1 was
identified and shown to be activated by both BZLF1 and BRLF1 but not by 12-O-…
identified and shown to be activated by both BZLF1 and BRLF1 but not by 12-O-…