Objetivo Caracterizar el proceso de implementación, barreras y facilitadores de recomendaciones
basadas en evidencia en el contexto del desarrollo de guías prácticas clínicas (GPC) …

Methods In developing this guideline, the steering committee followed standards for trustworthy
guidelines. 15 We included innovative approaches for key standards such as patient …

Objectives Clear communication of systematic review findings will help readers and decision
makers. We built on previous work to develop an approach that improves the clarity of …

Clinical decisions should be based on the totality of the best evidence and not the results of
individual studies. When clinicians apply the results of a systematic review or meta-analysis …

Background Guideline developers can: (1) adopt existing recommendations from others; (2)
adapt existing recommendations to their own context; or (3) create recommendations de …

Background An expert panel convened by the American Dental Association Council on Scientific
Affairs and the Center for Evidence-Based Dentistry conducted a systematic review and …

Importance The discontinuation of randomized clinical trials (RCTs) raises ethical concerns
and often wastes scarce research resources. The epidemiology of discontinued RCTs, …

Background This article presents evidence-based clinical recommendations for the use of pit-and-fissure
sealants on the occlusal surfaces of primary and permanent molars in children …

OBJECTIVE: We evaluated the inter-rater reliability (IRR) of assessing the quality of evidence
(QoE) using the Grading of Recommendations, Assessment, Development, and Evaluation …

Background: National Health and Nutrition Examination Survey 2011-2012 data indicated
that, in the United States, nearly onefourth of children and over one-half of adolescents …