Background We previously reported that there was no significant difference at 30 days or at
1 year in the rate of the composite outcome of death, stroke, myocardial infarction, or renal …

Background There is substantial variability in the perioperative administration of aspirin in
patients undergoing noncardiac surgery, both among patients who are already on an aspirin …

Background The relative benefits and risks of performing coronary-artery bypass grafting (CABG)
with a beating-heart technique (off-pump CABG), as compared with cardiopulmonary …

Background Previously, we reported that there was no significant difference at 30 days in
the rate of a primary composite outcome of death, myocardial infarction, stroke, or new renal …

Objectives : We conducted a randomized trial to assess the effectiveness of F-18-fluorodeoxyglucose
(FDG) positron emission tomography (PET)-assisted management in patients with …

Background Patients with peripheral artery disease have an increased risk of cardiovascular
morbidity and mortality. Antiplatelet agents are widely used to reduce these complications. …

Background Marked activation of the sympathetic nervous system occurs during and after
noncardiac surgery. Low-dose clonidine, which blunts central sympathetic outflow, may …

Background— Acute kidney injury (AKI) after cardiac surgery is a major health issue.
Lacking effective therapies, risk factor modification may offer a means of preventing this …

Importance Little is known about the relationship between perioperative high-sensitivity
troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac …

Background Surgical occlusion of the left atrial appendage has been hypothesized to
prevent ischemic stroke in patients with atrial fibrillation, but this has not been proved. The …