Procedural pain and brain development in premature newborns

…, R Brant, J Vinall, A Gover, AR Synnes… - Annals of …, 2012 - Wiley Online Library
Objective: Preterm infants are exposed to multiple painful procedures in the neonatal intensive
care unit (NICU) during a period of rapid brain development. Our aim was to examine …

Neonatal pain, parenting stress and interaction, in relation to cognitive and motor development at 8 and 18 months in preterm infants

RE Grunau, MF Whitfield, J Petrie-Thomas, AR Synnes… - Pain, 2009 - Elsevier
Procedural pain in the neonatal intensive care unit triggers a cascade of physiological,
behavioral and hormonal disruptions which may contribute to altered neurodevelopment in …

Variations in practice and outcomes in the Canadian NICU network: 1996–1997

…, DD McMillan, A Ohlsson, M Pendray, A Synnes… - …, 2000 - publications.aap.org
Background. Previous reports of variations in outcomes among neonatal intensive care
units (NICUs) examined only specific subpopulations of interest (eg, very low birth weight [VLBW] …

Incidence and outcomes of neonatal acute kidney injury (AWAKEN): a multicentre, multinational, observational cohort study

…, S Perazzo, PE Ray, M Revenis, A Synnes… - The lancet child & …, 2017 - thelancet.com
Background Findings from single-centre studies suggest that neonatal acute kidney injury (AKI)
is associated with poor outcomes. However, because of the small sample size of those …

Neurodevelopmental outcomes after cardiac surgery in infancy

…, NA Pike, C Pizarro, LS Shekerdemian, A Synnes… - …, 2015 - publications.aap.org
BACKGROUND: Neurodevelopmental disability is the most common complication for
survivors of surgery for congenital heart disease (CHD). METHODS: We analyzed individual …

[HTML][HTML] Neonatal pain-related stress predicts cortical thickness at age 7 years in children born very preterm

…, B Bjornson, K Poskitt, K Fitzpatrick, AR Synnes… - PloS one, 2013 - journals.plos.org
Background Altered brain development is evident in children born very preterm (24–32 weeks
gestational age), including reduction in gray and white matter volumes, and thinner cortex, …

Invasive procedures in preterm children: brain and cognitive development at school age

…, KPV Fitzpatrick, KJ Poskitt, R Brant, AR Synnes… - …, 2014 - publications.aap.org
BACKGROUND: Very preterm infants (born 24–32 weeks’ gestation) undergo numerous
invasive procedures during neonatal care. Repeated skin-breaking procedures in rodents …

Prediction of late death or disability at age 5 years using a count of 3 neonatal morbidities in very low birth weight infants

…, M Blayney, B Lemyre, J Frank, A Synnes… - The Journal of …, 2015 - Elsevier
Objective To evaluate bronchopulmonary dysplasia (BPD), serious brain injury, and severe
retinopathy of prematurity (ROP) as predictors of poor long-term outcome in very low birth …

Neonatal pain-related stress, functional cortical activity and visual-perceptual abilities in school-age children born at extremely low gestational age

…, AT Herdman, SP Miller, IL Cepeda, A Synnes… - PAIN®, 2013 - Elsevier
Children born very prematurely (⩽32 weeks) often exhibit visual-perceptual difficulties at
school-age, even in the absence of major neurological impairment. The alterations in functional …

Neonatal outcomes of very low birth weight and very preterm neonates: an international comparison

…, M Battin, D Bourchier, V Richardson, A Synnes… - The Journal of …, 2016 - Elsevier
Objective To compare rates of a composite outcome of mortality or major morbidity in very-preterm/very
low birth weight infants between 8 members of the International Network for …