The importance of frailty in the assessment of influenza vaccine effectiveness against influenza-related hospitalization in elderly people

…, JE McElhaney, A Ambrose… - The Journal of …, 2017 - academic.oup.com
Background Influenza is an important cause of morbidity and mortality among older adults.
Even so, effectiveness of influenza vaccine for older adults has been reported to be lower …

Effectiveness of influenza vaccination on hospitalizations and risk factors for severe outcomes in hospitalized patients with COPD

…, L Li, L Ye, T Hatchette, MK Andrew, A Ambrose… - Chest, 2019 - Elsevier
Background The effectiveness of influenza vaccination in reducing influenza-related
hospitalizations among patients with COPD is not well described, and influenza vaccination uptake …

Influenza vaccine effectiveness to prevent influenza-related hospitalizations and serious outcomes in Canadian adults over the 2011/12 through 2013/14 influenza …

MK Nichols, MK Andrew, TF Hatchette, A Ambrose… - Vaccine, 2018 - Elsevier
Background Ongoing assessment of influenza vaccine effectiveness (VE) is critical to inform
public health policy. This study aimed to determine the VE of trivalent influenza vaccine (TIV…

[HTML][HTML] Streptococcus pneumoniae serotype 3 is masking PCV13-mediated herd immunity in Canadian adults hospitalized with community acquired pneumonia: A …

…, M ElSherif, L Ye, D MacKinnon-Cameron, A Ambrose… - Vaccine, 2019 - Elsevier
Background The 13-valent pneumococcal conjugate vaccine (PCV13) was recently shown to
be effective against PCV13-type invasive pneumococcal disease (IPD) and pneumococcal …

Age-stratified burden of pneumococcal community acquired pneumonia in hospitalised Canadian adults from 2010 to 2015

…, D MacKinnon-Cameron, A Ambrose… - BMJ open …, 2020 - bmjopenrespres.bmj.com
Background In Canada, 13-valent pneumococcal conjugate vaccine (PCV13) is recommended
in childhood, in individuals at high risk of invasive pneumococcal disease (IPD) and in …

Resource utilization and cost of influenza requiring hospitalization in Canadian adults: A study from the serious outcomes surveillance network of the Canadian …

…, E Thommes, R Goeree, A Ambrose… - Influenza and Other …, 2018 - Wiley Online Library
Background Consideration of cost determinants is crucial to inform delivery of public
vaccination programs. Objectives To estimate the average total cost of laboratory‐confirmed …

[HTML][HTML] Recalibrated estimates of non-bacteremic and bacteremic pneumococcal community acquired pneumonia in hospitalized Canadian adults from 2010 to 2017 …

…, M ElSherif, L Ye, D MacKinnon-Cameron, A Ambrose… - Vaccine, 2022 - Elsevier
Objective(s) In the context of age- and risk-based pneumococcal vaccine recommendations
in Canada, this study presents updated data from active surveillance of pneumococcal …

Leveraging influenza virus surveillance from 2012 to 2015 to characterize the burden of respiratory syncytial virus disease in Canadian adults≥ 50 years of age …

M ElSherif, MK Andrew, L Ye, A Ambrose… - Open Forum …, 2023 - academic.oup.com
Background Respiratory syncytial virus (RSV) disease in older adults is undercharacterized.
To help inform future immunization policies, this study aimed to describe the disease …

[HTML][HTML] Burden of vaccine-preventable pneumococcal disease in hospitalized adults: A Canadian Immunization Research Network (CIRN) Serious Outcomes …

…, L Ye, D MacKinnon-Cameron, L Li, A Ambrose… - Vaccine, 2017 - Elsevier
Background Pneumococcal community acquired pneumonia (CAP Spn ) and invasive
pneumococcal disease (IPD) cause significant morbidity and mortality worldwide. Although …

[HTML][HTML] Influenza vaccine effectiveness against influenza-related hospitalization during a season with mixed outbreaks of four influenza viruses: a test-negative case …

MK Andrew, V Shinde, T Hatchette, A Ambrose… - BMC Infectious …, 2017 - Springer
Background The Serious Outcomes Surveillance (SOS) Network was established to monitor
seasonal influenza complications among hospitalized Canadian adults and to assess the …