Prospective analysis of sensitivity and specificity of urinary cytology and other urinary biomarkers for bladder cancer

FA Yafi, F Brimo, J Steinberg, AG Aprikian… - … oncology: seminars and …, 2015 - Elsevier
Introduction Although urinary cytology (C) is the most widely used noninvasive test for the
detection and surveillance of bladder cancer (BC), it has poor sensitivity especially for low-…

PTEN genomic deletion is associated with p‐Akt and AR signalling in poorer outcome, hormone refractory prostate cancer

…, G Chen, AD Darnel, AG Aprikian… - The Journal of …, 2009 - Wiley Online Library
PTEN haploinsufficiency is common in hormone‐sensitive prostate cancer, though the
incidence of genomic deletion and its downstream effects have not been elucidated in clinical …

Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50CSK in human metastatic prostate carcinoma

L Tremblay, W Hauck, AG Aprikian… - … Journal of Cancer, 1996 - Wiley Online Library
Pp125 FAK , a protein tyrosine kinase (PTK) co‐localized with integrins in focal adhesion
plaques, is known to transduce signals involved in the regulation of cell adhesion and motility …

Contemporary outcomes of 2287 patients with bladder cancer who were treated with radical cystectomy: a Canadian multicentre experience

FA Yafi, AG Aprikian, JL Chin, Y Fradet… - BJU …, 2011 - Wiley Online Library
Study Type – Therapy (case series) Level of Evidence 4 OBJECTIVE To evaluate data obtained
from a large, multi‐institutional, contemporary series of patients who underwent radical …

Development and validation of a nomogram predicting the outcome of prostate biopsy based on patient age, digital rectal examination and serum prostate specific …

…, H Heinzer, S Tanguay, AG Aprikian… - The Journal of …, 2005 - auajournals.org
Purpose : We developed and validated a nomogram which predicts presence of prostate
cancer (PCa) on needle biopsy. Materials and Methods : We used 3 cohorts of men who were …

Outcome of sextant biopsy according to gland volume

PI Karakiewicz, M Bazinet, AG Aprikian, C Trudel… - Urology, 1997 - Elsevier
OBJECTIVES: To reassess positive rate of sextant biopsy according to gland size. METHODS:
We evaluated 1974 consecutive men with systematic sextant biopsy, among whom we …

Characterization of neuroendocrine differentiation in human benign prostate and prostatic adenocarcinoma

AG Aprikian, C Cardon‐Cardo, WR Fair, VE Reuter - Cancer, 1993 - Wiley Online Library
Background. This report describes an immunohistopathologic analysis characterizing the
incidence, pattern of distribution, and hormonal content of neuroendocrine (NE) cells in human …

Delay in the surgical treatment of bladder cancer and survival: systematic review of the literature

NM Fahmy, S Mahmud, AG Aprikian - European urology, 2006 - Elsevier
OBJECTIVES: Eighty per cent of the newly diagnosed invasive bladder tumours are invasive
from the outset. Half of these patients already have occult distant metastases reflecting the …

Use of nonsteroidal anti‐inflammatory drugs and prostate cancer risk: a meta‐analysis

…, EL Franco, AG Aprikian - International journal of …, 2010 - Wiley Online Library
The association between use of aspirin and other nonsteroidal anti‐inflammatory drugs (NSAIDs)
and the risk of prostate cancer remains controversial despite many observational …

Active surveillance for selected patients with renal masses: updated results with long‐term follow‐up

T Abou Youssif, W Kassouf, J Steinberg, AG Aprikian… - Cancer, 2007 - Wiley Online Library
BACKGROUND. The objective of the current study was to evaluate the outcome of a surveillance
strategy in patients with renal masses. METHODS. The medical records of patients with …