Background This study evaluated the risk of long-term analgesic use after low-risk surgery
in older adults not previously prescribed analgesics. Methods We conducted a retrospective …

Ischemic mitral regurgitation (IMR) is a common complication of coronary artery disease
and is the focus of a rapidly increasing amount of research. Mechanistic studies have …

OBJECTIVE: Division of secondary chords (chordal cutting) has been proposed as a method
for decreasing mitral valve leaflet tethering and mitral regurgitation in patients with ischemic …

Hypothermia is present in up to two-thirds of patients with severe injury, although it is often
disregarded during the initial resuscitation. Studies have revealed that hypothermia is …

Purpose The objectives for preparing this article were to review the historical context and
epidemiology surrounding the North American prescription opioid crisis, to summarize the …

Transfusion-associated circulatory overload (TACO) is an important and potentially injurious
complication of transfusion that is underappreciated by clinicians. Risk factors for TACO …

Despite multimodal approaches to treatment, postpartum hemorrhage (PPH) is a life-threatening
condition whose incidence continues to rise. In developing areas, such as sub-Saharan …

Here, evidence suggests that nitric oxide synthases (NOS) of tumor cells, in contrast with
normal tissues, synthesize predominantly superoxide and peroxynitrite. Based on high-…

… Contributors: Asim Alam helped conceive the project and devise the study methodology,
oversaw the data collection, conducted the analyses, and was the principal writer of the …

Background: A massive hemorrhage protocol (MHP) enables rapid delivery of blood components
in a patient who is exsanguinating pending definitive hemorrhage control, but there is …