Background: Isotretinoin, a teratogen, is widely used to treat cystic acne. Although the risks of
pregnancy during isotretinoin therapy are well recognized, there are doubts about the level …

Importance Ondansetron is frequently used to treat nausea and vomiting during pregnancy.
Although some studies reported important safety signals, few studies have been sufficiently …

Introduction: We aimed to measure the impact of the COVID-19 pandemic on maternal
mental health, stratifying on pregnancy status, trimester of gestation, and pandemic period/wave. …

The effect of the COVID-19 pandemic on maternal mental health has been described in
Canada and China but no study has compared the two countries using the same standardized …

Background: Isotretinoin, for treating cystic acne, increases the risk of miscarriage and fetal
abnormalities when taken during pregnancy. The Health Canada–approved product …

Objectives The Canadian Index of Wellbeing (CIW) is an ambitious undertaking that aims to
measure and track Canadians’ overall “wellbeing”. The Healthy Populations, one of eight …

Background: Trends in off-label postpartum use of domperidone and the impact of safety
advisories on its use remain unknown. Our objectives were to describe postpartum use of …

Background Given that pregnant women taking medications are excluded from clinical trials,
real-world evidence is essential. We aimed to build a Canadian Mother-Child Cohort Active …

Objective To compare patterns in use of different antiemetics during pregnancy in Canada,
the United Kingdom, and the United States, between 2002 and 2014. Methods We …

Objective Little is known about physician support for prenatal screening. We sought a better
understanding of physicians’ values and opinions as they relate to prenatal screening, …