User profiles for Brendan Cord Lethebe
 | Brendan Cord LethebeUniversity Of Calgary Verified email at ucalgary.ca Cited by 1127 |
[HTML][HTML] Age-specific global epidemiology of hydrocephalus: Systematic review, metanalysis and global birth surveillance
Background Hydrocephalus is a debilitating disorder, affecting all age groups. Evaluation of
its global epidemiology is required for healthcare planning and resource allocation. …
its global epidemiology is required for healthcare planning and resource allocation. …
Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised …
…, A Poppe, A Sehgal, Q Zhang, BC Lethebe… - The Lancet, 2022 - thelancet.com
Background Intravenous thrombolysis with alteplase bolus followed by infusion is a global
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …
A randomized trial comparing high definition colonoscopy alone with high definition dye spraying and electronic virtual chromoendoscopy for detection of colonic …
…, R Panaccione, O Akinola, BC Lethebe… - Official journal of the …, 2018 - journals.lww.com
OBJECTIVES: Dye spraying chromoendoscopy (DCE) is recommended for the detection of
colonic neoplastic lesions in inflammatory bowel disease (IBD). The majority of neoplastic …
colonic neoplastic lesions in inflammatory bowel disease (IBD). The majority of neoplastic …
Development and reliability of the new endoscopic virtual chromoendoscopy score: the PICaSSO (Paddington International Virtual ChromoendoScopy ScOre) in …
…, M Goetz, M Lowerison, BC Lethebe… - Gastrointestinal …, 2017 - Elsevier
Background and Aims Endoscopic inflammation and healing are important therapeutic
endpoints in ulcerative colitis (UC). We developed and validated a new electronic virtual …
endpoints in ulcerative colitis (UC). We developed and validated a new electronic virtual …
Assessment of endoscopic healing by using advanced technologies reflects histological healing in ulcerative colitis
Background Several studies have reported that ulcerative colitis [UC] patients with endoscopic
mucosal healing may still have histological inflammation. We investigated the relationship …
mucosal healing may still have histological inflammation. We investigated the relationship …
[HTML][HTML] Prophylactic endoscopic clipping does not prevent delayed postpolypectomy bleeding in routine clinical practice: A propensity score–matched cohort study
METHODS: We manually reviewed records of patients who underwent polypectomy from 2008
to 2014 at a screening facility. Endoscopist-, patient-and polyp-related data were collected…
to 2014 at a screening facility. Endoscopist-, patient-and polyp-related data were collected…
Hyperchloremia and association with acute kidney injury in critically ill children
Background Hyperchloremia has been associated with acute kidney injury (AKI) in critically
ill adult patients. Data is limited in pediatric patients. Our study sought to determine if an …
ill adult patients. Data is limited in pediatric patients. Our study sought to determine if an …
[HTML][HTML] Developing and validating a primary care EMR-based frailty definition using machine learning
Objective The objective of this work is to develop and validate a case definition for frailty that
can be used in a primary care electronic medical record database. Methods This is a cross-…
can be used in a primary care electronic medical record database. Methods This is a cross-…
Impact of major depression and antidepressant use on alcoholic and non‐alcoholic fatty liver disease: A population‐based study
Background and Aims The effect of major depression and antidepressant use on patient
survival in chronic liver disease is unknown. We evaluated the impact of major depressive …
survival in chronic liver disease is unknown. We evaluated the impact of major depressive …
[HTML][HTML] Control of glycemia and blood pressure in British adults with diabetes mellitus and subsequent therapy choices: a comparison across health states
Background To examine the intensity of glycemic and blood pressure control in British adults
with diabetes mellitus and whether control levels or treatment deintensification rates differ …
with diabetes mellitus and whether control levels or treatment deintensification rates differ …