[HTML][HTML] TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells
BR Wong, J Rho, J Arron, E Robinson, J Orlinick… - Journal of Biological …, 1997 - ASBMB
A novel member of the tumor necrosis factor (TNF) cytokine family, designated TRANCE,
was cloned during a search for apoptosis-regulatory genes using a somatic cell genetic …
was cloned during a search for apoptosis-regulatory genes using a somatic cell genetic …
[HTML][HTML] Role of PFKFB3-driven glycolysis in vessel sprouting
…, M Georgiadou, S Schoors, A Kuchnio, BW Wong… - Cell, 2013 - cell.com
Vessel sprouting by migrating tip and proliferating stalk endothelial cells (ECs) is controlled
by genetic signals (such as Notch), but it is unknown whether metabolism also regulates this …
by genetic signals (such as Notch), but it is unknown whether metabolism also regulates this …
TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell–specific …
TRANCE (tumor necrosis factor [TNF]–related activation-induced cytokine) is a new member
of the TNF family that is induced upon T cell receptor engagement and activates c-Jun N-…
of the TNF family that is induced upon T cell receptor engagement and activates c-Jun N-…
Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles
E Bermudez, JB Mangum, BA Wong… - Toxicological …, 2004 - academic.oup.com
A multispecies, subchronic, inhalation study comparing pulmonary responses to ultrafine
titanium dioxide (uf-TiO 2 ) was performed. Female rats, mice, and hamsters were exposed to …
titanium dioxide (uf-TiO 2 ) was performed. Female rats, mice, and hamsters were exposed to …
[PDF][PDF] TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src
BR Wong, D Besser, N Kim, JR Arron, M Vologodskaia… - Molecular cell, 1999 - cell.com
TRANCE, a TNF family member, and its receptor, TRANCE-R, are critical regulators of
dendritic cell and osteoclast function. Here, we demonstrate that TRANCE activates the …
dendritic cell and osteoclast function. Here, we demonstrate that TRANCE activates the …
TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts
K Fuller, B Wong, S Fox, Y Choi… - The Journal of …, 1998 - rupress.org
TRANCE (tumor necrosis factor–related activation-induced cytokine) is a recently described
member of the tumor necrosis factor superfamily that stimulates dendritic cell survival and …
member of the tumor necrosis factor superfamily that stimulates dendritic cell survival and …
Multiple myeloma disrupts the TRANCE/osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression
…, EM Sordillo, S Yaccoby, BR Wong… - Proceedings of the …, 2001 - National Acad Sciences
Bone destruction, caused by aberrant production and activation of osteoclasts, is a prominent
feature of multiple myeloma. We demonstrate that myeloma stimulates osteoclastogenesis …
feature of multiple myeloma. We demonstrate that myeloma stimulates osteoclastogenesis …
[HTML][HTML] The TRAF family of signal transducers mediates NF-κB activation by the TRANCE receptor
Tumor necrosis factor (TNF)-related activation-induced cytokine (TRANCE), a member of
the TNF family expressed on activated T-cells, bone marrow stromal cells, and osteoblasts, …
the TNF family expressed on activated T-cells, bone marrow stromal cells, and osteoblasts, …
[HTML][HTML] Evidence for a role of a tumor necrosis factor-α (TNF-α)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in …
Tumor necrosis factor (TNF)-related activation-induced cytokine (TRANCE), a member of
the TNF family, is a dendritic cell survival factor and is essential for osteoclastogenesis and …
the TNF family, is a dendritic cell survival factor and is essential for osteoclastogenesis and …
R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation
…, K Qu, E Herlaar, A Lau, C Young, BR Wong… - … of Pharmacology and …, 2006 - ASPET
Recent compelling evidence has lead to renewed interest in the role of antibodies and
immune complexes in the pathogenesis of several autoimmune disorders, such as rheumatoid …
immune complexes in the pathogenesis of several autoimmune disorders, such as rheumatoid …