Background There is substantial variability in the perioperative administration of aspirin in
patients undergoing noncardiac surgery, both among patients who are already on an aspirin …

Importance Little is known about the relationship between perioperative high-sensitivity
troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac …

Background There is a need to increase access to surgical treatments in African countries,
but perioperative complications represent a major global health-care burden. There are few …

Background Myocardial injury after non-cardiac surgery (MINS) increases the risk of
cardiovascular events and deaths, which anticoagulation therapy could prevent. Dabigatran …

Background Marked activation of the sympathetic nervous system occurs during and after
noncardiac surgery. Low-dose clonidine, which blunts central sympathetic outflow, may …

Objectives : The objective of this study was to determine whether measuring post-operative
B-type natriuretic peptides (NPs) (ie, B-type natriuretic peptide [BNP] and N-terminal …

Background There have been insufficient data for African patients with COVID-19 who are
critically ill. The African COVID-19 Critical Care Outcomes Study (ACCCOS) aimed to …

Background Observational studies have suggested that accelerated surgery is associated
with improved outcomes in patients with a hip fracture. The HIP ATTACK trial assessed …

BACKGROUND: Among adults undergoing contemporary noncardiac surgery, little is
known about the frequency and timing of death and the associations between perioperative …

Background Maternal and neonatal mortality is high in Africa, but few large, prospective
studies have been done to investigate the risk factors associated with these poor maternal and …