[HTML][HTML] A Predominantly Clonal Multi-Institutional Outbreak of Clostridium difficile–Associated Diarrhea with High Morbidity and Mortality

…, AM Bourgault, T Nguyen, C Frenette… - … England Journal of …, 2005 - Mass Medical Soc
Background In March 2003, several hospitals in Quebec, Canada, noted a marked increase
in the incidence of Clostridium difficile–associated diarrhea. Methods In 2004 we conducted …

Continuous proton pump inhibitor therapy and the associated risk of recurrent Clostridium difficile infection

EG McDonald, J Milligan, C Frenette… - JAMA internal …, 2015 - jamanetwork.com
Importance Clostridium difficileinfection (CDI) is associated with significant morbidity, mortality,
and a high risk of recurrence. Proton pump inhibitor (PPI) use is associated with an initial …

The evolving epidemiology of Clostridium difficile infection in Canadian hospitals during a postepidemic period (2009–2015)

…, JC Collet, I Davis, T Du, GA Evans, C Frenette… - Cmaj, 2018 - Can Med Assoc
Background: The clinical and molecular epidemiology of health care–associated Clostridium
difficile infection in nonepidemic settings across Canada has evolved since the first report …

Medical masks versus N95 respirators for preventing COVID-19 among health care workers: a randomized trial

…, S Mansour, LA Castellucci, C Frenette… - Annals of internal …, 2022 - acpjournals.org
Background: It is uncertain if medical masks offer similar protection against COVID-19 compared
with N95 respirators. Objective: To determine whether medical masks are noninferior to …

Antibiotic self-stewardship: trainee-led structured antibiotic time-outs to improve antimicrobial use

TC Lee, C Frenette, D Jayaraman, L Green… - Annals of internal …, 2014 - acpjournals.org
Background: Antibiotic use is an important quality improvement target. Nearly 50% of antibiotic
use is unnecessary or inappropriate. To combat overuse, the Centers for Disease Control …

Multiplex respiratory virus testing for antimicrobial stewardship: a prospective assessment of antimicrobial use and clinical outcomes among hospitalized adults

…, I Schiller, BA Jardin, C Frenette… - The Journal of …, 2017 - academic.oup.com
Background Respiratory tract infections are frequent causes of hospitalization and initiation
of empirical antimicrobial therapy. Testing for a broad panel of respiratory viruses has been …

Healthcare-associated influenza in Canadian hospitals from 2006 to 2012

G Taylor, R Mitchell, A McGeer, C Frenette… - Infection Control & …, 2014 - cambridge.org
Objective.To determine trends, patient characteristics, and outcome of patients with
healthcare-associated influenza in Canadian hospitals.Design.Prospective surveillance of laboratory-…

Healthcare-associated infections in the neurological intensive care unit: results of a 6-year surveillance study at a major tertiary care center

…, I Schiller, N Dendukuri, MR Angle, C Frenette - American journal of …, 2018 - Elsevier
Background Healthcare-associated infections (HAIs) occur frequently in neurological
intensive care units (neuro-ICUs); however, data differentiating associations with various …

Trends in health care–associated infections in acute care hospitals in Canada: an analysis of repeated point-prevalence surveys

…, S Alexandre, K Bush, L Forrester, C Frenette… - Cmaj, 2019 - Can Med Assoc
BACKGROUND: Health care–associated infections are a common cause of patient morbidity
and mortality. We sought to describe the trends in these infections in acute care hospitals, …

Seasonal variations in Clostridium difficile infections are associated with influenza and respiratory syncytial virus activity independently of antibiotic prescriptions: a …

R Gilca, É Fortin, C Frenette, Y Longtin… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Seasonal variations in Clostridium difficile -associated diarrhea (CDAD), with a higher
incidence occurring during winter months, have been reported. Although winter epidemics of …