Aims Novel oral anticoagulants (NOACs) are alternatives to vitamin‐K antagonists (VKAs) for
the prevention of thromboembolism. It is unclear how NOACs have been adopted in the UK …

Importance Selective serotonin reuptake inhibitors (SSRIs) may increase the risk for
spontaneous intracranial hemorrhage (ICH), an effect that is in theory linked to the strength of …

BACKGROUND: Some evidence indicates that androgen-deprivation therapy (ADT) increases
the risk of diabetes and cardiovascular disease. To date, few studies have investigated …

Objectives To determine the risk of stroke associated with oral and transdermal routes of
administration of hormone replacement therapy. Design Population based nested case-control …

Background The course and prognosis of childhood-onset multiple sclerosis have not been
well described. Methods We used data from 13 adult neurology departments affiliated with …

Aims An increased risk of stroke was observed in two atrial fibrillation (AF) trials of oral factor
Xa inhibitors, when patients were transitioned to open label warfarin at the end of the study. …

Objectives To report the third case of subacute cerebellar ataxia associated with metabotropic
glutamate receptor type 1 autoantibodies (mGluR1-Abs), an uncommon syndrome known …

Methods| Using the Clinical Practice Research Datalink (CPRD), a UK database of primary
care medical records from more than 15 million patients, 5 we identified all patients …

Objective To assess whether the use of dipeptidyl peptidase-4 inhibitors is associated with
the incidence of inflammatory bowel disease in patients with type 2 diabetes. Design …

Aim The aim of the present study was to describe the prescription of medications for
attention‐deficit hyperactivity disorder (ADHD) in the UK between 1995 and 2015. Methods Using …