Importance Single-center studies identify frailty as a risk factor for 30-day postoperative
mortality. The long-term and population-level effect of frailty on postoperative mortality is, to our …

Background: Substantial health inequities exist for Indigenous Peoples in Canada. The remote
and distributed population of Canada presents unique challenges for access to and use …

Background and Objectives Frailty leaves older adults vulnerable to adverse health outcomes.
Frailty assessment is recommended by multiple COVID‐19 guidelines to inform care and …

Background Evidence-based international expert consensus regarding the impact of
peripheral nerve block (PNB) use in total hip/knee arthroplasty surgery. Methods A systematic …

Background Cancer is common in older adults, who often have concurrent frailty. Frailty is a
strong predictor of adverse outcomes in surgical patients. Our objective is to systematically …

Background The certainty that prehabilitation improves postoperative outcomes is not clear.
The objective of this umbrella review (ie systematic review of systematic reviews) was to …

Frailty is a multidimensional syndrome characterized by decreased reserve and diminished
resistance to stressors. People with frailty are vulnerable to stressors, and exposure to the …

Background A barrier to routine preoperative frailty assessment is the large number of frailty
instruments described. Previous systematic reviews estimate the association of frailty with …

Objective: To compare the accuracy of the modified Fried Index (mFI) and the Clinical Frailty
Scale (CFS) to predict death or patient-reported new disability 90 days after major elective …

… , and Daniel McIsaac, Karim Abdulla and Alan Forster contributed to study design. Daniel
McIsaac, … Daniel McIsaac wrote the manuscript, with contributions from Karim Abdulla and Alan …