Objective: The objective was to provide guidelines to clinicians for the evaluation, treatment,
and prevention of vitamin D deficiency with an emphasis on the care of patients who are at …

ContextVertebral fractures significantly increase lifetime risk of future fractures, but risk of
further vertebral fractures in the period immediately following a vertebral fracture has not been …

This work provides a systematic review of the literature from January 2003 to April 2014
pertaining to the incidence, pathophysiology, diagnosis, and treatment of osteonecrosis of the …

Since the publication of the Osteoporosis Canada guide-lines in 2002, there has been a
paradigm shift in the prevention and treatment of osteoporosis and fractures. 1, 2 The focus now …

All therapies currently recommended for the management of osteoporosis act mainly to
inhibit bone resorption and reduce bone remodeling. PTH and its analog, teriparatide […

Background: The Medical Outcomes Study 36-item Short Form (SF-36) is a widely used
measure of health-related quality of life. Normative data are the key to determining whether a …

Vitamin D is currently a topic of intense interest to the scientific and lay communities. Recently
a committee convened by the Institute of Medicine (IOM) released a report identifying …

The amino-bisphosphonates are first-line therapy for the treatment of most patients with
osteoporosis, with proven efficacy to reduce fracture risk at the spine, hip, and other nonvertebral …

Background: Fractures have largely been assessed by their impact on quality of life or health
care costs. We conducted this study to evaluate the relation between fractures and mortality…

Background: Recombinant human parathyroid hormone (1-84) (PTH) increases bone mass
and strength and improves bone quality by stimulating new bone formation. Objective: To …