The pathogenesis of primary mediastinal large B-cell lymphoma (PMBCL) is incompletely
understood. Recently, specific genotypic and phenotypic features have been linked to tumor …

Primary testicular lymphomas (PTL) are the most prevalent type of testicular cancer arising
in men over the age of 60. PTL accounts for approximately 1–2% of all non-Hodgkin …

Primary testicular diffuse large B cell lymphoma ( PTL ) is an aggressive malignancy that
occurs in the immune‐privileged anatomical site of the testis. We have previously shown that …

Programmed death ligands (PDLs) are immune-regulatory molecules that are frequently
affected by chromosomal alterations in B-cell lymphomas. Although PDL copy-number …

Primary mediastinal large B-cell lymphoma (PMBCL) is an aggressive non-Hodgkin lymphoma
that displays phenotypic and genotypic similarity to Hodgkin lymphoma and diffuse large …

Background Angiotensin converting enzyme 2 (ACE2) protein serves as the host receptor
for SARS-CoV-2, with a critical role in viral infection. We aim to understand population level …

Clinical investigators within the Canadian and international communities were shocked when
the Canadian Institutes of Health Research (CIHR) announced that their funding for the MD…

COI notes: KJS Consulting and honoraria: Bristol-Myers Squibb, Merck, Seattle Genetics, Astra
Zeneca, Gilead, Abbvie. Consulting: Servier. Steering committee: Beignet. CS Consulting …

In this study, we evaluate the impact of whole genome and transcriptome analysis (WGTA)
on predictive molecular profiling and histologic diagnosis in a cohort of advanced …

Tumour‐promoting inflammation is an emerging hallmark of cancer that is increasingly
recognised as a therapeutic target. As a constituent measure of inflammation, tumour‐infiltrating …