User profiles for Denise Mak

Denise Mak

Senior Data Scientist, Optum
Verified email at optum.com
Cited by 21

[HTML][HTML] Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort …

…, LL Lam, H Xie, NJ Harding, DYF Mak… - The lancet …, 2014 - thelancet.com
Background Clinical prognostic groupings for localised prostate cancers are imprecise, with
30–50% of patients recurring after image-guided radiotherapy or radical prostatectomy. We …

[HTML][HTML] BPG: Seamless, automated and interactive visualization of scientific data

…, SD Prokopec, M Shamsi, F Nguyen, DYF Mak… - BMC …, 2019 - Springer
Background We introduce BPG, a framework for generating publication-quality, highly-customizable
plots in the R statistical environment. Results This open-source package includes …

Assessing the quality of clinical and administrative data extracted from hospitals: the General Medicine Inpatient Initiative (GEMINI) experience

…, HY Jung, V Kushnir, DYF Mak… - Journal of the …, 2021 - academic.oup.com
Objective Large clinical databases are increasingly used for research and quality
improvement. We describe an approach to data quality assessment from the General Medicine …

[HTML][HTML] Ethnicity impacts the cystic fibrosis diagnosis: a note of caution

…, D Bilton, P Sosnay, KS Raraigh, DYF Mak… - Journal of Cystic …, 2017 - Elsevier
Background The diagnosis of Cystic Fibrosis (CF) is by consensus based on the same
parameters in all patients, yet the influence of ethnicity has only scarcely been studied. We aimed …

Indel seeds for homology search

D Mak, Y Gelfand, G Benson - Bioinformatics, 2006 - academic.oup.com
We are interested in detecting homologous genomic DNA sequences with the goal of locating
approximate inverted, interspersed, and tandem repeats. Standard search techniques …

[PDF][PDF] Allele-skewed DNA modification in the brain: relevance to a schizophrenia GWAS

SA Gagliano, C Ptak, DYF Mak, M Shamsi, G Oh… - The American Journal of …, 2016 - cell.com
Numerous recent studies have suggested that phenotypic effects of DNA sequence variants
can be mediated or modulated by their epigenetic marks, such as allele-skewed DNA …

Probing for multilingual numerical understanding in transformer-based language models

D Johnson, D Mak, D Barker… - arXiv preprint arXiv …, 2020 - arxiv.org
Natural language numbers are an example of compositional structures, where larger numbers
are composed of operations on smaller numbers. Given that compositional reasoning is a …

Modelling resource requirements and physician staffing to provide virtual urgent medical care for residents of long-term care homes: a cross-sectional study

…, A Weinerman, S Rawal, V Kushnir, D Mak… - … Open Access Journal, 2020 - cmajopen.ca
Background: The coronavirus disease 2019 (COVID-19) outbreak increases the importance
of strategies to enhance urgent medical care delivery in long-term care (LTC) facilities that …

NLPStatTest: a toolkit for comparing NLP system performance

H Zhu, D Mak, J Gioannini, F Xia - arXiv preprint arXiv:2011.13231, 2020 - arxiv.org
Statistical significance testing centered on p-values is commonly used to compare NLP
system performance, but p-values alone are insufficient because statistical significance differs …

All hits all the time: parameter-free calculation of spaced seed sensitivity

DYF Mak, G Benson - Bioinformatics, 2009 - academic.oup.com
Motivation: Standard search techniques for DNA repeats start by identifying small matching
words, or seeds, that may inhabit larger repeats. Recent innovations in seed structure …