Objective To determine the diagnostic accuracy of serological tests for coronavirus disease-2019
(covid-19). Design Systematic review and meta-analysis. Data sources Medline, …

Background Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic,
expensive, and has generally poor outcomes. We undertook an individual patient data meta-…

Background The study objective was to conduct a systematic review and meta-analysis on
the proportion of asymptomatic infection among coronavirus disease 2019 (COVID-19) …

Background: Interferon-γ–release assays (IGRAs) are alternatives to the tuberculin skin test (TST).
A recent meta-analysis showed that IGRAs have high specificity, even among …

Background: Until recently, the tuberculin skin test was the only test for detecting latent
tuberculosis (TB) infection, but 2 ex vivo interferon-γ release assays (IGRAs) are now …

Major adverse reactions to antituberculosis drugs can cause significant morbidity, and
compromise treatment regimens for tuberculosis (TB). Among patients treated for active TB we …

Background Treatment of latent Mycobacterium tuberculosis infection is an essential component
of tuberculosis control and elimination. The current standard regimen of isoniazid for 9 …

Background The risk of transmission of Mycobacterium tuberculosis from patients to health-care
workers (HCWs) is a neglected problem in many low- and middle-income countries (…

Background: Antibiotic disruption of the normal intestinal flora is a well-known risk factor for
Clostridium difficile-associated diarrhea. Reduced gastric acidity has been suggested as a …

The tuberculin skin test is one of the few tests developed in the 19th century that is still in
present use in clinical medicine. The first tuberculin test material was prepared by Robert Koch (…