User profiles for Dirk Westermann

Dirk Westermann

University heart center, hamburg
Verified email at uke.de
Cited by 21145

Utility of Doppler echocardiography and tissue Doppler imaging in the estimation of diastolic function in heart failure with normal ejection fraction: a comparative …

M Kasner, D Westermann, P Steendijk, R Gaub… - Circulation, 2007 - Am Heart Assoc
Background— Various conventional and tissue Doppler echocardiographic indexes were
compared with pressure–volume loop analysis to assess their accuracy in detecting left …

Diastolic tissue Doppler indexes correlate with the degree of collagen expression and cross-linking in heart failure and normal ejection fraction

M Kasner, D Westermann, B Lopez, R Gaub… - Journal of the American …, 2011 - jacc.org
Objectives : We attempted to correlate echocardiographic analysis of diastolic function with
changes of myocardial collagen in middle-aged patients with heart failure (HF) despite …

Pretreatment with statin attenuates the cardiotoxicity of Doxorubicin in mice

A Riad, S Bien, D Westermann, PM Becher, K Loya… - Cancer research, 2009 - AACR
Cardiotoxicity, which may result from intense cardiac oxidative stress and inflammation, is
the main limiting factor of the anticancer therapy using doxorubicin. Because statins might …

Cardiac inflammation contributes to changes in the extracellular matrix in patients with heart failure and normal ejection fraction

D Westermann, D Lindner, M Kasner… - Circulation: Heart …, 2011 - Am Heart Assoc
Background— The pathophysiology of heart failure with normal ejection fraction (HFNEF) is
still under discussion. Here we report the influence of cardiac inflammation on extracellular …

Role of left ventricular stiffness in heart failure with normal ejection fraction

D Westermann, M Kasner, P Steendijk, F Spillmann… - Circulation, 2008 - Am Heart Assoc
Background— Increased left ventricular stiffness is a distinct finding in patients who have
heart failure with normal ejection fraction (HFNEF). To elucidate how diastolic dysfunction …

Contributions of inflammation and cardiac matrix metalloproteinase activity to cardiac failure in diabetic cardiomyopathy: the role of angiotensin type 1 receptor …

D Westermann, S Rutschow, S Jager, A Linderer… - Diabetes, 2007 - Am Diabetes Assoc
We investigated the effect of the angiotensin type 1 (AT-1) receptor antagonist, irbesartan,
on matrix metalloproteinase (MMP) activity and cardiac cytokines in an animal model of …

Association of cardiac infection with SARS-CoV-2 in confirmed COVID-19 autopsy cases

…, S Blankenberg, K Püschel, D Westermann - JAMA …, 2020 - jamanetwork.com
Importance Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be
documented in various tissues, but the frequency of cardiac involvement as well as possible …

Left ventricular unloading is associated with lower mortality in patients with cardiogenic shock treated with venoarterial extracorporeal membrane oxygenation: results …

…, F Tietz, A Varshney, L Wechsler, D Westermann - Circulation, 2020 - Am Heart Assoc
Background: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly
used to treat cardiogenic shock. However, VA-ECMO might hamper myocardial recovery. …

Concomitant implantation of Impella® on top of veno‐arterial extracorporeal membrane oxygenation may improve survival of patients with cardiogenic shock

…, A Zangrillo, D Westermann - European journal of …, 2017 - Wiley Online Library
Aims Veno‐arterial extracorporeal membrane oxygenation ( VA‐ECMO ) support stabilizes
patients with cardiogenic shock. Despite improved oxygenation and peripheral circulation, …

Atrial shunt device for heart failure with preserved and mildly reduced ejection fraction (REDUCE LAP-HF II): a randomised, multicentre, blinded, sham-controlled trial

…, T Wengenmayer, R Westenfeld, D Westermann… - The Lancet, 2022 - thelancet.com
Background Placement of an interatrial shunt device reduces pulmonary capillary wedge
pressure during exercise in patients with heart failure and preserved or mildly reduced ejection …