Effect of screening with primary cervical HPV testing vs cytology testing on high-grade cervical intraepithelial neoplasia at 48 months: the HPV FOCAL randomized …
GS Ogilvie, D van Niekerk, M Krajden, LW Smith… - Jama, 2018 - jamanetwork.com
Importance There is limited information about the relative effectiveness of cervical cancer
screening with primary human papillomavirus (HPV) testing alone compared with cytology in …
screening with primary human papillomavirus (HPV) testing alone compared with cytology in …
The path to eliminating cervical cancer in Canada: past, present and future directions
H Caird, J Simkin, L Smith, D Van Niekerk, G Ogilvie - Current Oncology, 2022 - mdpi.com
Cervical cancer remains a common cancer affecting women in Canada. While cervical cancer
incidence and mortality in Canada have declined for several decades due to the success …
incidence and mortality in Canada have declined for several decades due to the success …
Screening for the prevention and early detection of cervical cancer: protocol for systematic reviews to inform Canadian recommendations
Purpose To inform recommendations by the Canadian Task Force on Preventive Health Care
on screening in primary care for the prevention and early detection of cervical cancer by …
on screening in primary care for the prevention and early detection of cervical cancer by …
HPV for cervical cancer screening (HPV FOCAL): Complete Round 1 results of a randomized trial comparing HPV‐based primary screening to liquid‐based cytology …
GS Ogilvie, M Krajden, D van Niekerk… - … journal of cancer, 2017 - Wiley Online Library
Complete Round 1 data (baseline and 12‐month follow‐up) for HPV FOCAL, a randomized
trial establishing the efficacy of HPV DNA testing with cytology triage as a primary screen for …
trial establishing the efficacy of HPV DNA testing with cytology triage as a primary screen for …
Primary hrHPV DNA testing in cervical cancer screening: how to manage screen-positive women? A POBASCAM trial substudy
…, D van Niekerk, DC Rijkaart, FJ van Kemenade… - … , biomarkers & prevention, 2014 - AACR
Background: High-risk human papillomavirus (hrHPV) testing has higher sensitivity but lower
specificity than cytology for cervical (pre)-cancerous lesions. Therefore, triage of hrHPV-…
specificity than cytology for cervical (pre)-cancerous lesions. Therefore, triage of hrHPV-…
A randomized controlled trial of H uman P apilloma v irus (HPV) testing fo rc ervic al cancer screening: trial design and preliminary results (HPV FOCAL Trial)
GS Ogilvie, DJ van Niekerk, M Krajden, RE Martin… - BMC cancer, 2010 - Springer
Background In the HPV FOCAL trial, we will establish the efficacy of hr-HPV DNA testing as
a stand-alone screening test followed by liquid based cytology (LBC) triage of hr-HPV-…
a stand-alone screening test followed by liquid based cytology (LBC) triage of hr-HPV-…
Community-integrated self-collected HPV-based cervix screening in a low-resource rural setting: a pragmatic, cluster-randomized trial
…, PN Simelela, J Singer, LW Smith, D Van Niekerk… - Nature Medicine, 2023 - nature.com
Effective approaches to improve coverage of self-collected human papillomavirus (HPV)-based
cervix screening (SCS) as well as attendance at treatment for HPV-positive participants …
cervix screening (SCS) as well as attendance at treatment for HPV-positive participants …
Evaluation of a validated methylation triage signature for human papillomavirus positive women in the HPV FOCAL cervical cancer screening trial
…, JH Law, LW Smith, DJ van Niekerk… - … Journal of Cancer, 2019 - Wiley Online Library
Human papillomavirus (HPV)‐based cervical cancer screening requires triage of HPV
positive women to identify those at risk of cervical intraepithelial neoplasia grade 2 (CIN2) or …
positive women to identify those at risk of cervical intraepithelial neoplasia grade 2 (CIN2) or …
Automatic labeling of molecular biomarkers of immunohistochemistry images using fully convolutional networks
F Sheikhzadeh, RK Ward, D van Niekerk, M Guillaud - PloS one, 2018 - journals.plos.org
This paper addresses the problem of quantifying biomarkers in multi-stained tissues based
on the color and spatial information of microscopy images of the tissue. A deep learning-…
on the color and spatial information of microscopy images of the tissue. A deep learning-…
Women's intentions to receive cervical cancer screening with primary human papillomavirus testing
GS Ogilvie, LW Smith, DJ van Niekerk… - … journal of cancer, 2013 - Wiley Online Library
We explored the potential impact of human papillomavirus (HPV) testing on women's intentions
to be screened for cervical cancer in a cohort of Canadian women. Participants aged 25–…
to be screened for cervical cancer in a cohort of Canadian women. Participants aged 25–…