Background Therapies to interrupt the progression of early coronavirus disease 2019 (Covid-19)
remain elusive. Among them, convalescent plasma administered to hospitalized …

OBJECTIVE: To propose a tool to assist trialists in making design decisions that are consistent
with their trial's stated purpose. STUDY DESIGN AND SETTING: Randomized trials have …

Background: Cesarean section rates show a wide variation among countries in the world,
ranging from 0.4 to 40 percent, and a continuous rise in the trend has been observed in the …

Background. Calcium supplementation has been reported to reduce blood pressure in pregnant
and nonpregnant women. We undertook this prospective study to determine the effect of …

Background Bed rest in hospital or at home is widely recommended for the prevention of
preterm birth. This advice is based on the observation that hard work and hard physical activity …

Objectives. To examine the association between high prepregnancy maternal body mass
index (BMI) and the risk of preterm birth (PTB). Methods. A systematic review of the literature. …

Background Latin America has a high rate of caesarean sections. We tested the hypothesis
that a hospital policy of mandatory second opinion, based on the best existing scientific …

Preeclampsia is a pregnancy-specific condition that increases maternal and infant mortality
and morbidity. It is diagnosed by new-onset increased blood pressure and proteinuria during …

Background Active management of the third stage of labour reduces the risk of post-partum
haemorrhage. We aimed to assess whether controlled cord traction can be omitted from …

Background Implementation of evidence-based obstetrical practices remains a significant
challenge. Effective strategies to disseminate and implement such practices are needed. …