The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement,
published in 2009, was designed to help systematic reviewers transparently report why …

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
COVID-19 and is spread person-to-person through close contact. We aimed to investigate the …

Objective To develop a new evidence‐based, pharmacologic treatment guideline for rheumatoid
arthritis (RA). Methods We conducted systematic reviews to synthesize the evidence for …

Scoping reviews, a type of knowledge synthesis, follow a systematic approach to map evidence
on a topic and identify main concepts, theories, sources, and knowledge gaps. Although …

The methods and results of systematic reviews should be reported in sufficient detail to allow
users to assess the trustworthiness and applicability of the review findings. The Preferred …

This article is the first of a series providing guidance for use of the Grading of Recommendations
Assessment, Development, and Evaluation (GRADE) system of rating quality of …

Background We update recommendations on 12 topics that were in the 9th edition of these
guidelines, and address 3 new topics. Methods We generate strong (Grade 1) and weak (…

Background This article addresses the treatment of VTE disease. Methods We generated
strong (Grade 1) and weak (Grade 2) recommendations based on high-quality (Grade A), …

Objective To develop updated guidelines for the pharmacologic management of rheumatoid
arthritis. Methods We developed clinically relevant population, intervention, comparator, …

In the GRADE approach, randomized trials start as high-quality evidence and observational
studies as low-quality evidence, but both can be rated down if most of the relevant evidence …