Proton pump inhibitors and the risk of acute kidney injury in older patients: a population-based cohort study
T Antoniou, EM Macdonald, S Hollands… - … Open Access Journal, 2015 - cmajopen.ca
Background Proton pump inhibitors (PPIs) cause interstitial nephritis and are an underappreciated
cause of acute kidney injury. We examined the risk of acute kidney injury and acute …
cause of acute kidney injury. We examined the risk of acute kidney injury and acute …
[HTML][HTML] A 1980 letter on the risk of opioid addiction
PTM Leung, EM Macdonald… - … England Journal of …, 2017 - Mass Medical Soc
A 1980 Letter on the Risk of Opioid Addiction | NEJM Skip to main content NEJM Group Follow
Us Facebook Twitter Instagram YouTube LinkedIn Prepare to become a physician, build your …
Us Facebook Twitter Instagram YouTube LinkedIn Prepare to become a physician, build your …
Risk of suicide following deliberate self-poisoning
Y Finkelstein, EM Macdonald, S Hollands… - JAMA …, 2015 - jamanetwork.com
Importance Suicide is the tenth leading cause of death in the United States, and its rate has
risen by 16% in the past decade. Deliberate self-poisoning is the leading method of …
risen by 16% in the past decade. Deliberate self-poisoning is the leading method of …
Co-trimoxazole and sudden death in patients receiving inhibitors of renin-angiotensin system: population based study
M Fralick, EM Macdonald, T Gomes, T Antoniou… - Bmj, 2014 - bmj.com
Objective To determine whether the prescription of co-trimoxazole with an angiotensin
converting enzyme inhibitor or angiotensin receptor blocker is associated with sudden death. …
converting enzyme inhibitor or angiotensin receptor blocker is associated with sudden death. …
Long-term outcomes following self-poisoning in adolescents: a population-based cohort study
Y Finkelstein, EM Macdonald, S Hollands… - The Lancet …, 2015 - thelancet.com
Background Suicide is the third most common cause of death among adolescents worldwide,
and poisoning is the leading method of attempted suicide. Unlike more violent methods, …
and poisoning is the leading method of attempted suicide. Unlike more violent methods, …
[HTML][HTML] Proton pump inhibitors and hospitalization with hypomagnesemia: a population-based case-control study
Background Some evidence suggests that proton pump inhibitors (PPIs) are an under-appreciated
risk factor for hypomagnesemia. Whether hospitalization with hypomagnesemia is …
risk factor for hypomagnesemia. Whether hospitalization with hypomagnesemia is …
Overdose risk in young children of women prescribed opioids
Y Finkelstein, EM Macdonald, A Gonzalez… - …, 2017 - publications.aap.org
METHODS: We conducted a population-based, nested case control study in Ontario,
Canada, between 2002 and 2015. We identified children aged≤ 10 years, whose mothers …
Canada, between 2002 and 2015. We identified children aged≤ 10 years, whose mothers …
Trimethoprim–sulfamethoxazole and risk of sudden death among patients taking spironolactone
Background: Trimethoprim–sulfamethoxazole increases the risk of hyperkalemia when used
with spironolactone. We examined whether this drug combination is associated with an …
with spironolactone. We examined whether this drug combination is associated with an …
[HTML][HTML] Predictors of opioid-related death during methadone therapy
We aimed to examine pharmacologic, demographic and medical comorbidity risk factors for
opioid-related mortality among patients currently receiving methadone for an opioid use …
opioid-related mortality among patients currently receiving methadone for an opioid use …
Association between statin use and ischemic stroke or major hemorrhage in patients taking dabigatran for atrial fibrillation
T Antoniou, EM Macdonald, Z Yao, S Hollands… - Cmaj, 2017 - Can Med Assoc
BACKGROUND: Dabigatran etexilate is a prodrug whose absorption is opposed by intestinal
P-glycoprotein and which is converted by carboxylesterase to its active form, dabigatran. …
P-glycoprotein and which is converted by carboxylesterase to its active form, dabigatran. …