Cannabis use in pregnancy has increased 1 , 2 , and many women continue to use it throughout
pregnancy 3 . With the legalization of recreational cannabis in many jurisdictions, there …

BACKGROUND: Many studies have shown that depression increases mortality risk. We aimed
to investigate the duration of time over which depression is associated with increased risk …

Rationale & Objective Renin-angiotensin-aldosterone system (RAAS) inhibitors are
evidence-based therapies that slow the progression of chronic kidney disease (CKD) but can cause …

Objectives: The purpose of the present study was to assess longitudinal associations
between positive and harsh parenting in childhood and adolescent mental and behavioral …

Importance Clarithromycin is a commonly prescribed antibiotic associated with higher levels
of direct oral anticoagulants (DOACs) in the blood, with the potential to increase the risk of …

Background Frailty is a geriatric syndrome that leaves people vulnerable to adverse
outcomes. In cardiac surgery, minimal data describe associations between frailty and patient-…

Background Lack of appropriate temperature management has been associated with
significant adverse outcomes in preterm and low birthweight neonates. There is a lack of similar …

Background Routinely used cardiac medications, based on pharmacokinetics, are
hypothesized to increase drug levels of direct oral anticoagulants (DOACs), with the potential to …

Le vieillissement des populations s’est considérablement accentué ces dernières décennies
et ce plus particulièrement pour la population francophone vivant en situation linguistique …

METHODS: Population-based retrospective cohort study conducted in Ontario, Canada using
multiple linked province-wide health administrative databases. All live births between April …