Background Perioperative bleeding is common in patients undergoing noncardiac surgery.
Tranexamic acid is an antifibrinolytic drug that may safely decrease such bleeding. Methods …

Background The effect on cardiovascular outcomes of withholding angiotensin-converting
enzyme inhibitors or angiotensin II receptor blockers in chronic users before noncardiac …

Background Observational studies have suggested that accelerated surgery is associated
with improved outcomes in patients with a hip fracture. The HIP ATTACK trial assessed …

Background In non-surgical settings, covert stroke is more common than overt stroke and is
associated with cognitive decline. Although overt stroke occurs in less than 1% of adults after …

Background: Preliminary data suggest that preoperative N-terminal pro–B-type natriuretic
peptide (NT-proBNP) may improve risk prediction in patients undergoing noncardiac surgery. …

Background: Among patients having noncardiac surgery, perioperative hemodynamic
abnormalities are associated with vascular complications. Uncertainty remains about what …

Background Consensus recommendations regarding the threshold levels of cardiac troponin
elevations for the definition of perioperative myocardial infarction and clinically important …

Background Higher levels of inflammatory biomarkers are associated with an increased risk
of perioperative atrial fibrillation and myocardial injury after non-cardiac surgery (MINS). …

Objective To determine if virtual care with remote automated monitoring (RAM) technology
versus standard care increases days alive at home among adults discharged after non-…

Background Benzodiazepine use is associated with delirium, and guidelines recommend
avoiding them in older and critically ill patients. Their perioperative use remains common …