User profiles for Giada Sebastiani

Giada Sebastiani

Professor of Medicine, McGill University
Verified email at mcgill.ca
Cited by 10211

Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: systematic review and meta‐analysis

…, M Soni, LJ Prokop, Z Younossi, G Sebastiani… - Hepatology, 2017 - journals.lww.com
Liver fibrosis is the most important predictor of mortality in nonalcoholic fatty liver disease (NAFLD).
Quantitative risk of mortality by fibrosis stage has not been systematically evaluated. …

[HTML][HTML] Association between fibrosis stage and outcomes of patients with nonalcoholic fatty liver disease: a systematic review and meta-analysis

…, VWS Wong, N Peleg, A Shlomai, G Sebastiani… - Gastroenterology, 2020 - Elsevier
Background & Aims Biopsy-confirmed liver fibrosis is a prognostic factor for patients with
nonalcoholic fatty liver disease (NAFLD). We performed a systematic review to quantify the …

[HTML][HTML] Non invasive fibrosis biomarkers reduce but not substitute the need for liver biopsy

G Sebastiani, A Alberti - World journal of gastroenterology: WJG, 2006 - ncbi.nlm.nih.gov
Chronic liver diseases are very common worldwide, particularly those linked to viral hepatitis
and to alcoholic and non-alcoholic fatty liver. Their natural history is variable and long-term …

Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C

G Sebastiani, A Vario, M Guido, F Noventa… - Journal of …, 2006 - Elsevier
BACKGROUND/AIMS: In chronic hepatitis C, biopsy is the gold standard for assessment of
liver fibrosis. Non-invasive markers have been proposed but their use is limited by diagnostic …

[HTML][HTML] Chronic hepatitis C and liver fibrosis

G Sebastiani, K Gkouvatsos… - World journal of …, 2014 - ncbi.nlm.nih.gov
Chronic infection with hepatitis C virus (HCV) is a leading cause of liver-related morbidity
and mortality worldwide and predisposes to liver fibrosis and end-stage liver complications. …

Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C

L Castéra, G Sebastiani, B Le Bail, V de Lédinghen… - Journal of …, 2010 - Elsevier
BACKGROUND & AIMS: Non-invasive assessment of liver fibrosis is a challenging area.
Several methods have been proposed in patients with chronic hepatitis C (CHC) but their …

Liver fibrosis: Review of current imaging and MRI quantification techniques

L Petitclerc, G Sebastiani, G Gilbert… - Journal of Magnetic …, 2017 - Wiley Online Library
Liver fibrosis is characterized by the accumulation of extracellular matrix proteins such as
collagen in the liver interstitial space. All causes of chronic liver disease may lead to fibrosis …

2019 update of the European AIDS Clinical Society Guidelines for treatment of people living with HIV version 10.0

…, E Negredo, N Poulter, P Reiss, G Sebastiani… - HIV …, 2020 - Wiley Online Library
Background The European AIDS Clinical Society (EACS) Guidelines cover key aspects of
HIV management with major updates every two years. Guideline highlights The 2019 …

[PDF][PDF] SAFE biopsy: a validated method for large‐scale staging of liver fibrosis in chronic hepatitis C

G Sebastiani, P Halfon, L Castera, S Pol… - …, 2009 - Wiley Online Library
The staging of liver fibrosis is pivotal for defining the prognosis and indications for therapy in
hepatitis C. Although liver biopsy remains the gold standard, several noninvasive methods …

[HTML][HTML] Limitations of non-invasive tests for assessment of liver fibrosis

K Patel, G Sebastiani - JHEP Reports, 2020 - Elsevier
The diagnostic assessment of liver injury is an important step in the management of patients
with chronic liver disease (CLD). Although liver biopsy is the reference standard for the …