User profiles for Gillian A. Lowe

Gillian Lowe

The University of the West Indies, Mona.
Verified email at uwimona.edu.jm
Cited by 761

Utility of the ISTH bleeding assessment tool in predicting platelet defects in participants with suspected inherited platelet function disorders

GC Lowe, M Lordkipanidze, SP Watson… - … of Thrombosis and …, 2013 - Wiley Online Library
Background The ISTH bleeding assessment tool ( ISTH ‐ BAT ) was developed to record
bleeding symptoms and to aid diagnosis in patients with a possible bleeding disorder. …

[HTML][HTML] Whole exome sequencing identifies genetic variants in inherited thrombocytopenia with secondary qualitative function defects

B Johnson, GC Lowe, J Futterer, M Lordkipanidzé… - …, 2016 - ncbi.nlm.nih.gov
Inherited thrombocytopenias are a heterogeneous group of disorders characterized by
abnormally low platelet counts which can be associated with abnormal bleeding. Next-generation …

Enrichment of FLI1 and RUNX1 mutations in families with excessive bleeding and platelet dense granule secretion defects

…, NV Morgan, D Bem, GC Lowe… - Blood, The Journal …, 2013 - ashpublications.org
We analyzed candidate platelet function disorder genes in 13 index cases with a history of
excessive bleeding in association with a significant reduction in dense granule secretion and …

Evaluation of participants with suspected heritable platelet function disorders including recommendation and validation of a streamlined agonist panel

BB Dawood, GC Lowe, M Lordkipanidzé… - Blood, The Journal …, 2012 - ashpublications.org
Light transmission aggregometry (LTA) is used worldwide for the investigation of heritable
platelet function disorders (PFDs), but interpretation of results is complicated by the feedback …

[HTML][HTML] Parenting and depressive symptoms among adolescents in four Caribbean societies

G Lipps, GA Lowe, RC Gibson, S Halliday… - Child and adolescent …, 2012 - Springer
Background The strategies that parents use to guide and discipline their children may
influence their emotional health. Relatively little research has been conducted examining the …

Rituximab prophylaxis to prevent thrombotic thrombocytopenic purpura relapse: outcome and evaluation of dosing regimens

…, S Benjamin, WA Lester, GC Lowe… - Blood …, 2017 - ashpublications.org
Acute antibody-mediated thrombotic thrombocytopenic purpura (TTP) is a thrombotic
microangiopathy with high morbidity and mortality. Rituximab is highly effective as prophylaxis in …

[HTML][HTML] SLFN14 mutations underlie thrombocytopenia with excessive bleeding and platelet secretion defects

SJ Fletcher, B Johnson, GC Lowe… - The Journal of …, 2015 - Am Soc Clin Investig
Inherited thrombocytopenias are a group of disorders that are characterized by a low platelet
count and are sometimes associated with excessive bleeding that ranges from mild to …

[HTML][HTML] Parenting styles, anxiety and depressive symptoms in child/adolescent

…, L Gómez-de-Regil, GA Lowe… - International journal of …, 2021 - scielo.org.co
Gillian A. Lowe 3 … A medium effect size was chosen for the sample size calculations based
on past research using Caribbean samples ( Lipps et al., 2012 ; Lowe et al., 2009 ). Results of …

Characterization of multiple platelet activation pathways in patients with bleeding as a high-throughput screening option: use of 96-well Optimul assay

M Lordkipanidzé, GC Lowe, NS Kirkby… - Blood, The Journal …, 2014 - ashpublications.org
Up to 1% of the population have mild bleeding disorders, but these remain poorly characterized,
particularly with regard to the roles of platelets. We have compared the usefulness of …

Mutation in GNE is associated with severe congenital thrombocytopenia

J Futterer, A Dalby, GC Lowe, B Johnson… - Blood, The Journal …, 2018 - ashpublications.org
Inherited thrombocytopenias are associated with bleeding of all types of severity depending
on the reduction in platelet count and whether there is altered platelet function. 1 The normal …