Time of day-dependent variations of immune system parameters are ubiquitous phenomena
in immunology. The circadian clock has been attributed with coordinating these variations …

Activation of innate immune receptors by host-derived factors exacerbates CNS damage, but
the identity of these factors remains elusive. We uncovered an unconventional role for the …

Microglial cells closely interact with senile plaques in Alzheimer’s disease and acquire the
morphological appearance of an activated phenotype. The significance of this microglial …

Ambivalent effects of interleukin-6 on the pathogenesis of ischaemic stroke have been
reported. However, to date, the long-term actions of interleukin-6 after stroke have not been …

E500 CMAJ, December 6, 2016, 188 (17–18) secret. A US survey in 1993 found that none
of the representatives of 29 academic health centres viewed their selection system as “open.” …

Background: Attention-deficit/hyperactivity disorder (ADHD), a common neurodevelopmental
condition now recognized to persist into older adulthood, has been postulated to be a risk …

MATERIALS AND METHODS Strains. The supplied strains were labeled as S. typhimurium
strains LT2 (wild-type), TA98 (hisD3052, ΔuvrB, rfa, pKM101) and TA100 (hisG46, ΔuvrB, rfa, …

… 1 , Gina D Eom …

… (EOM) is a rare middle ear disease with unfavorable outcomes. Under the current diagnostic
criteria of EOM, it is challenging to suspect EOM … the differential diagnosis of EOM from other …

Background Despite the fact that Abeta (Aβ)-targeted immunotherapy is a major hope for
treatment of Alzheimer's disease (AD), the mechanism of antibody-mediated clearance of Aβ …